About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tcrb
T cell receptor beta chain
MGI:98578
22 phenotypes from 20 alleles in 13 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
TcrbLn3Jae/Tcrb+
B6.Cg-TcrbLn3Jae 		abnormal double-negative T cell morphology J:143006
absent gamma-delta T cells J:143006
Tcrbtm1Habu/Tcrbtm1Habu
involves: C57BL/6 * CBA 		no abnormal phenotype detected J:84291
Tcrbtm1Mom/Tcrbtm1Mom
B6;129P2-Tcrbtm1Mom/J 		abnormal respiratory system physiology J:125656
Tcrbtm1Mom/Tcrbtm1Mom
involves: 129P2/OlaHsd * BALB/c 		arrested T cell differentiation J:3206
colitis J:15221
decreased CD4-positive, alpha-beta T cell number J:3206
decreased CD8-positive, alpha-beta T cell number J:3206
decreased double-positive T cell number J:3206
thymus hypoplasia J:3206
Tcrbtm1Slek/Tcrbtm1Slek
Not Specified 		normal immune system phenotype J:119552
Tcrbtm1Slek/Tcrbtm5Slek
Not Specified 		abnormal T cell receptor beta chain V(D)J recombination J:143738
Tcrbtm1Slek/Tcrbtm6Slek
Not Specified 		abnormal T cell receptor beta chain V(D)J recombination J:143738
Tcrbtm2(Tcrb)Fwa/Tcrbtm3Slek
involves: 129 		abnormal T cell receptor beta chain V(D)J recombination J:132446
Tcrbtm2Slek/Tcrbtm2Slek
Not Specified 		arrested T cell differentiation J:119552
decreased T cell number J:119552
Tcrbtm3.1Che/Tcrbtm3.1Che
involves: 129S4/SvJae 		normal immune system phenotype J:120387
Tcrbtm3Che/Tcrbtm3Che
involves: 129S4/SvJae 		normal immune system phenotype J:120387
Tcrbtm3Slek/Tcrbtm3Slek
Not Specified 		arrested T cell differentiation J:119552
decreased T cell number J:119552
Tcrbtm4Slek/Tcrbtm4Slek
Not Specified 		normal immune system phenotype J:119552
Tcrbtm5Slek/Tcrbtm5Slek
Not Specified 		abnormal T cell receptor beta chain V(D)J recombination J:143738
Tcrbtm6Slek/Tcrbtm6Slek
Not Specified 		abnormal T cell receptor beta chain V(D)J recombination J:143738
Tcrbtm7Slek/Tcrbtm7Slek
Not Specified 		abnormal T cell receptor beta chain V(D)J recombination J:143738
Tcrbtm8.1Slek/Tcrbtm8.1Slek
Not Specified 		normal immune system phenotype J:176070
Tcrbtm9.1Slek/Tcrbtm9.1Slek
Not Specified 		normal immune system phenotype J:176070
Tg(H2-K-TcrbP14)128Mak/?
involves: C57BL/6 * C57L * DBA/2 		abnormal CD8-positive, alpha-beta T cell differentiation J:111265
abnormal T cell clonal deletion J:111265
abnormal T cell differentiation J:111265
increased CD8-positive, alpha-beta T cell number J:111265
Tg(Tcrb)93Vbo/0
involves: C57BL/6 * C57BL/LiA * CBA/BrA 		abnormal CD8-positive, alpha-beta T cell differentiation J:66565
abnormal cytotoxic T cell physiology J:66565
abnormal T cell clonal deletion J:66565
Tg(Tcrb)93Vbo/0
involves: C57BL/LiA * CBA/BrA 		abnormal T cell morphology J:93247
abnormal T cell receptor beta chain V(D)J recombination J:93247
Tg(Tcrb)HRBAll/0
B6.Cg-Tg(Tcrb)HRBAll 		normal immune system phenotype J:131347
Tg(TcrbAI4)1Dvs/0
NOD-Tg(TcrbAI4)1Dvs 		abnormal CD4-positive, alpha beta T cell morphology J:93553
abnormal circulating glucose level J:93553
Tg(TcrbBL17)1Lmor/0
involves: DBA/1J * SWR/J 		increased susceptibility to induced arthritis J:134111
Tg(TcrbBL17)1Lmor/Tg(TcrbBL17)1Lmor
involves: DBA/1J * SWR/J 		increased susceptibility to induced arthritis J:134111
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory