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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tcrb
T cell receptor beta chain
MGI:98578
22 phenotypes from 20 alleles in 13 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
TcrbLn3Jae/Tcrb+
B6.Cg-TcrbLn3Jae 		abnormal double-negative T cell morphology J:143006
absent gamma-delta T cells J:143006
Tcrbtm1Habu/Tcrbtm1Habu
involves: C57BL/6 * CBA 		no abnormal phenotype detected J:84291
Tcrbtm1Mom/Tcrbtm1Mom
B6;129P2-Tcrbtm1Mom/J 		abnormal respiratory system physiology J:125656
Tcrbtm1Mom/Tcrbtm1Mom
involves: 129P2/OlaHsd * BALB/c 		arrested T cell differentiation J:3206
colitis J:15221
decreased CD4-positive, alpha-beta T cell number J:3206
decreased CD8-positive, alpha-beta T cell number J:3206
decreased double-positive T cell number J:3206
thymus hypoplasia J:3206
Tcrbtm1Slek/Tcrbtm1Slek
Not Specified 		normal immune system phenotype J:119552
Tcrbtm1Slek/Tcrbtm5Slek
Not Specified 		abnormal T cell receptor beta chain V(D)J recombination J:143738
Tcrbtm1Slek/Tcrbtm6Slek
Not Specified 		abnormal T cell receptor beta chain V(D)J recombination J:143738
Tcrbtm2(Tcrb)Fwa/Tcrbtm3Slek
involves: 129 		abnormal T cell receptor beta chain V(D)J recombination J:132446
Tcrbtm2Slek/Tcrbtm2Slek
Not Specified 		arrested T cell differentiation J:119552
decreased T cell number J:119552
Tcrbtm3.1Che/Tcrbtm3.1Che
involves: 129S4/SvJae 		normal immune system phenotype J:120387
Tcrbtm3Che/Tcrbtm3Che
involves: 129S4/SvJae 		normal immune system phenotype J:120387
Tcrbtm3Slek/Tcrbtm3Slek
Not Specified 		arrested T cell differentiation J:119552
decreased T cell number J:119552
Tcrbtm4Slek/Tcrbtm4Slek
Not Specified 		normal immune system phenotype J:119552
Tcrbtm5Slek/Tcrbtm5Slek
Not Specified 		abnormal T cell receptor beta chain V(D)J recombination J:143738
Tcrbtm6Slek/Tcrbtm6Slek
Not Specified 		abnormal T cell receptor beta chain V(D)J recombination J:143738
Tcrbtm7Slek/Tcrbtm7Slek
Not Specified 		abnormal T cell receptor beta chain V(D)J recombination J:143738
Tcrbtm8.1Slek/Tcrbtm8.1Slek
Not Specified 		normal immune system phenotype J:176070
Tcrbtm9.1Slek/Tcrbtm9.1Slek
Not Specified 		normal immune system phenotype J:176070
Tg(H2-K-TcrbP14)128Mak/?
involves: C57BL/6 * C57L * DBA/2 		abnormal CD8-positive, alpha-beta T cell differentiation J:111265
abnormal T cell clonal deletion J:111265
abnormal T cell differentiation J:111265
increased CD8-positive, alpha-beta T cell number J:111265
Tg(Tcrb)93Vbo/0
involves: C57BL/6 * C57BL/LiA * CBA/BrA 		abnormal CD8-positive, alpha-beta T cell differentiation J:66565
abnormal cytotoxic T cell physiology J:66565
abnormal T cell clonal deletion J:66565
Tg(Tcrb)93Vbo/0
involves: C57BL/LiA * CBA/BrA 		abnormal T cell morphology J:93247
abnormal T cell receptor beta chain V(D)J recombination J:93247
Tg(Tcrb)HRBAll/0
B6.Cg-Tg(Tcrb)HRBAll 		normal immune system phenotype J:131347
Tg(TcrbAI4)1Dvs/0
NOD-Tg(TcrbAI4)1Dvs 		abnormal CD4-positive, alpha beta T cell morphology J:93553
abnormal circulating glucose level J:93553
Tg(TcrbBL17)1Lmor/0
involves: DBA/1J * SWR/J 		increased susceptibility to induced arthritis J:134111
Tg(TcrbBL17)1Lmor/Tg(TcrbBL17)1Lmor
involves: DBA/1J * SWR/J 		increased susceptibility to induced arthritis J:134111
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory