Epha4 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Epha4
Eph receptor A4
MGI:98277

15 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
\Chn1^Gt714Lex/\Chn1⁺ \Epha4^tm1Pch/\Epha4⁺ involves: 129S2/SvPas * 129S5/SvEvBrd	abnormal gait	J:128698
	abnormal spinal cord dorsal column morphology	J:128698
	abnormal spinal cord interneuron morphology	J:128698
\Chn1^tm1.1Ece/\Chn1^tm1.1Ece \Epha4^tm1.2Bzh/\Epha4^tm1.2Bzh \Tg(Hlxb9-GFP)1Tmj/0 involves: 129S/Sv * C57BL/6J * CD-1 * FVB/N	abnormal innervation	J:243785
\Chn1^tm1.2Ece/\Chn1⁺ \Epha4^tm1.2Bzh/\Epha4^tm1.2Bzh \Tg(Hlxb9-GFP)1Tmj/0 involves: 129S/Sv * C57BL/6J * CD-1 * FVB/N	abnormal abducens nerve morphology	J:243785
	abnormal innervation	J:243785
\Chn1^tm1.2Ece/\Chn1^tm1.2Ece \Epha4^tm1.2Bzh/\Epha4^tm1.2Bzh \Tg(Hlxb9-GFP)1Tmj/0 involves: 129S/Sv * C57BL/6J * CD-1 * FVB/N	abnormal abducens nerve morphology	J:243785
	abnormal innervation	J:243785
\Epha4^{Gt(PST038)Byg}/\Epha4^{Gt(PST038)Byg} \Ret^tm1.1Kln/\Ret^tm1.1Kln involves: 129/Sv * BALB/c * C57BL/6 * CBA/J	abnormal axon guidance	J:110955
	abnormal innervation pattern to muscle	J:110955
\Epha4^tm1Kln/\Epha4^tm1Kln involves: 129P2/OlaHsd * C57BL/6	normal behavior/neurological phenotype	J:67274
	normal nervous system phenotype	J:67274
\Epha4^tm2Kln/\Epha4⁺ involves: 129P2/OlaHsd * C57BL/6	abnormal barrel cortex morphology	J:115279
	abnormal innervation	J:115279
	abnormal primary somatosensory cortex morphology	J:115279
\Epha4^tm2Kln/\Epha4^tm2Kln involves: 129P2/OlaHsd * C57BL/6	abnormal barrel cortex morphology	J:115279
	abnormal gait	J:67274, J:101019
	abnormal innervation	J:115279
	abnormal primary somatosensory cortex morphology	J:115279
	abnormal spinal cord dorsal column morphology	J:101019
\Epha4^tm3Kln/\Epha4^tm3Kln involves: 129P2/OlaHsd * C57BL/6	abnormal corticospinal tract morphology	J:67274
	abnormal gait	J:67274
\Epha4^tm4Kln/\Epha4^tm4Kln involves: 129P2/OlaHsd * C57BL/6	normal nervous system phenotype	J:115279
	no abnormal phenotype detected	J:67274
\Epha4^tm6Kln/\Epha4^tm6Kln involves: 129/Sv * C57BL/6	abnormal barrel cortex morphology	J:115279
	abnormal innervation	J:115279
	abnormal primary somatosensory cortex morphology	J:115279
\Epha4^tm6Kln/\Epha4^tm6Kln involves: 129S/SvEv * C57BL/6	abnormal central pattern generator function	J:101019
\Epha4^tm6Kln/\Epha4^tm6Kln involves: 129S/SvEv * C57BL/6	ectopic thalamus	J:101019

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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