P4hb Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

P4hb
prolyl 4-hydroxylase, beta polypeptide
MGI:97464

10 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
P4hb^tm1.1Geno/P4hb^tm1.1Geno Tg(Mx1-cre)1Cgn/0 involves: 129 * C57BL/6 * C57BL/6J * CBA/J	decreased platelet aggregation	J:229395
	decreased susceptibility to induced thrombosis	J:229395
	normal hematopoietic system phenotype	J:229395
P4hb^tm1.1Geno/P4hb^tm1.1Geno Tg(Pf4-icre)Q3Rsko/0 involves: 129 * C57BL/6	abnormal platelet dense granule physiology	J:229395
	decreased platelet aggregation	J:229395
	decreased susceptibility to induced thrombosis	J:229395
	normal hematopoietic system phenotype	J:229395
	increased bleeding time	J:229395
P4hb^tm1.1Geno/P4hb^tm1.2Geno Lyz2^tm1(cre)Ifo/Lyz2⁺ involves: 129P2/OlaHsd	decreased neutrophil cell number	J:197556
	impaired neutrophil recruitment	J:197556
P4hb^{tm1b(KOMP)Wtsi}/P4hb^{tm1b(KOMP)Wtsi} C57BL/6N-P4hb^{tm1b(KOMP)Wtsi}/MbpMmucd	embryonic growth retardation	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
P4hb^{tm1b(KOMP)Wtsi}/P4hb^{tm1b(KOMP)Wtsi} C57BL/6N-P4hb^{tm1b(KOMP)Wtsi}/Ucd	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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