About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ngfr
nerve growth factor receptor (TNFR superfamily, member 16)
MGI:97323
72 phenotypes from 6 alleles in 14 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Ngfrtm1.1Vk/Ngfrtm1.1Vk
involves: 129S2/SvPas * FVB/N
no abnormal phenotype detected J:178666
Ngfrtm1.1Vk/Ngfrtm1.1Vk
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S2/SvPas * C57BL/6J * CBA/J * FVB/N
abnormal sciatic nerve morphology J:178666
normal cardiovascular system phenotype J:178666
normal growth/size/body region phenotype J:178666
limb grasping J:178666
Ngfrtm1.2Vk/Ngfrtm1.2Vk
involves: 129S2/SvPas * FVB/N
limb grasping J:178666
postnatal growth retardation J:178666
Ngfrtm1a(EUCOMM)Wtsi/Ngfr+
C57BL/6N-Ngfrtm1a(EUCOMM)Wtsi/Ics
decreased circulating alkaline phosphatase level J:165965
Ngfrtm1b(EUCOMM)Wtsi/Ngfr+
C57BL/6N-Ngfrtm1b(EUCOMM)Wtsi/H
limb grasping J:211773
Ngfrtm1b(EUCOMM)Wtsi/Ngfrtm1b(EUCOMM)Wtsi
C57BL/6N-Ngfrtm1b(EUCOMM)Wtsi/H
abnormal behavior J:211773
abnormal digit morphology J:211773
abnormal gait J:211773
decreased locomotor activity J:211773
decreased thigmotaxis J:211773
increased circulating phosphate level J:211773
limb grasping J:211773
preweaning lethality, incomplete penetrance J:211773
tremors J:211773
Ngfrtm1Gdc/Ngfrtm1Gdc
involves: 129X1/SvJ * C57BL/6
abnormal blood vessel morphology J:71955
abnormal gait J:71955
abnormal L5 dorsal root ganglion morphology J:71955
abnormal posture J:71955
abnormal sciatic nerve morphology J:71955
ataxia J:71955
decreased body size J:71955
decreased Schwann cell number J:71955
dilated dorsal aorta J:71955
hemorrhage J:71955
perinatal lethality, incomplete penetrance J:71955
Ngfrtm1Jae/Ngfr+
B6.129S4-Ngfrtm1Jae
abnormal axon extension J:127639
abnormal neuron differentiation J:127639
decreased airway responsiveness J:115419
Ngfrtm1Jae/Ngfrtm1Jae
B6.129S4-Ngfrtm1Jae
abnormal axon extension J:127639
abnormal circumvallate papillae morphology J:90280
abnormal gustatory papilla taste bud morphology J:90280
abnormal innervation pattern to muscle J:90280
abnormal Kupffer cell morphology J:120368
abnormal neuron differentiation J:127639
abnormal neuron morphology J:128451
abnormal sensory neuron innervation pattern J:90280
abnormal tongue epithelium morphology J:90280
abnormal vascular wound healing J:109753
increased neuron number J:128451
increased retina photoreceptor cell number J:115542
increased susceptibility to experimental autoimmune encephalomyelitis J:112769
Ngfrtm1Jae/Ngfrtm1Jae
B6.129S4-Ngfrtm1Jae/J
cochlear ganglion degeneration J:110434
cochlear hair cell degeneration J:110434
decreased myocardial infarct size J:190893
increased or absent threshold for auditory brainstem response J:110434
increased susceptibility to age-related hearing loss J:110434
organ of Corti degeneration J:110434
sensorineural hearing loss J:110434
Ngfrtm1Jae/Ngfrtm1Jae
C;129S-Ngfrtm1Jae/J
abnormal neuron apoptosis J:46125
Ngfrtm1Jae/Ngfrtm1Jae
involves: 129 * BALB/c
abnormal axon extension J:96121
Ngfrtm1Jae/Ngfrtm1Jae
involves: 129S1/Sv * 129S4/SvJae
abnormal retina ganglion cell morphology J:145459
abnormal superior colliculus morphology J:145459
Ngfrtm1Jae/Ngfrtm1Jae
involves: 129S4/SvJae
abnormal axon guidance J:145459
abnormal cholinergic neuron morphology J:62379
abnormal eye physiology J:157549
abnormal retina ganglion cell morphology J:145459
abnormal sensory neuron innervation pattern J:43749
abnormal spatial learning J:62379
abnormal superior colliculus morphology J:145459
abnormal trigeminal ganglion morphology J:157604
abnormal tumor necrosis factor level J:157549
decreased neuron apoptosis J:123022
Ngfrtm1Jae/Ngfrtm1Jae
involves: 129S4/SvJae * BALB/c
abnormal dorsal root ganglion morphology J:53825
abnormal molar crown morphology J:42087
abnormal molar morphology J:42087
abnormal muscle morphology J:53825
abnormal oral cavity morphology J:42087
abnormal proprioceptive neuron morphology J:53825
abnormal sensory capabilities/reflexes/nociception J:43748
abnormal sensory neuron innervation pattern J:42087, J:43748
abnormal tooth morphology J:42087
absent hair follicles J:43748
decreased muscle spindle number J:53825
extremity edema J:43748
normal renal/urinary system phenotype J:43748
small L4 dorsal root ganglion J:53825
ulcerated autopod J:43748
Ngfrtm1Jae/Ngfrtm1Jae
involves: 129S4/SvJae * C57BL/6
abnormal axon extension J:139381
abnormal axon pruning J:139381
Ngfrtm1Jae/Ngfrtm1Jae
involves: 129S4/SvJae * C57BL/6J
abnormal peripheral nervous system regeneration J:116954
decreased motor neuron number J:116954

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory