Nek1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nek1
NIMA (never in mitosis gene a)-related expressed kinase 1
MGI:97303

43 phenotypes from 3 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nek1^em1(IMPC)Bay/Nek1^em1(IMPC)Bay C57BL/6N-Nek1^em1(IMPC)Bay/Bay	abnormal bone structure	J:211773
	abnormal cranium morphology	J:211773
	abnormal pelvic girdle bone morphology	J:211773
	abnormal retina outer nuclear layer morphology	J:211773
	decreased body length	J:211773
	decreased bone mineral content	J:211773
	decreased cardiac stroke volume	J:211773
	decreased grip strength	J:211773
	decreased prepulse inhibition	J:211773
	decreased total retina thickness	J:211773
	male infertility	J:211773
	short tibia	J:211773
Nek1^kat-2J/Nek1^kat-2J C57BL/6J-Nek1^kat-2J/J	abnormal cerebral aqueduct morphology	J:37799
	abnormal choroid plexus morphology	J:37799
	abnormal craniofacial morphology	J:37799
	abnormal olfactory bulb morphology	J:37799
	abnormal renal tubule morphology	J:134248
	abnormal spermatogenesis	J:59839
	anemia	J:37799, J:59839
	decreased birth body size	J:37799
	decreased body length	J:59839
	decreased body size	J:59839
	dilated fourth ventricle	J:37799
	dilated lateral ventricle	J:37799
	dilated third ventricle	J:37799
	increased blood urea nitrogen level	J:59839
	kidney cortex cyst	J:37799
	kidney cyst	J:37799
	male infertility	J:37799
	obstructive hydrocephaly	J:37799
	poikilocytosis	J:59839
	polycystic kidney	J:37799, J:59839
	premature death	J:59839
	reduced female fertility	J:37799
	short snout	J:37799, J:59839
	shortened head	J:37799
	small olfactory bulb	J:37799
	small testis	J:37799
	testis hypoplasia	J:59839
Nek1^kat/Nek1^kat B6.RBF(C3Fe)-Nek1^kat/J	decreased body size	J:37799
	domed cranium	J:37799
	postnatal lethality, incomplete penetrance	J:37799
	proportional dwarf	J:37799
Nek1^kat/Nek1^kat involves: C3HeB/FeJLe * C57BL/6J * RBF/Dn	abnormal cerebral aqueduct morphology	J:37799
	abnormal choroid plexus morphology	J:37799
	abnormal craniofacial morphology	J:59839
	abnormal erythrocyte osmotic lysis	J:59839
	abnormal olfactory bulb morphology	J:37799
	anemia	J:59839
	decreased body length	J:59839
	decreased body size	J:59839
	dilated fourth ventricle	J:37799
	dilated lateral ventricle	J:37799
	dilated third ventricle	J:37799
	kidney cortex cyst	J:37799, J:59839
	kidney cyst	J:37799, J:59839
	obstructive hydrocephaly	J:37799
	polycystic kidney	J:37799, J:59839
	premature death	J:59839
	short snout	J:59839
	shortened head	J:59839
	small olfactory bulb	J:37799
Nek1^kat/Nek1^kat involves: C3HeB/FeJLe * RBF/Dn	decreased body length	J:37799
	decreased body size	J:37799
	male infertility	J:37799
	premature death	J:37799
	reduced female fertility	J:37799
Nek1^kat/Nek1^kat involves: RBF/Dn	decreased body length	J:37799
	decreased body size	J:37799
	domed cranium	J:37799
	kidney cyst	J:37799
	postnatal lethality	J:37799
	premature death	J:37799
	sparse hair	J:37799

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23