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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Lmna
lamin A
MGI:96794
28 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
ApcMin/Apc+
Lmnatm4Stw/Lmnatm4Stw
Tg(Vil1-cre)997Gum/0
involves: C57BL/6 * C57BL/6J 		duodenum polyps J:220874
jejunum polyps J:220874
Lmnatm1.1Otin/Lmna+
Nat10tm1a(KOMP)Wtsi/Nat10+
involves: 129P2/OlaHsd * C57BL/6NTac 		decreased body weight J:261974
kyphosis J:261974
premature death J:261974
Lmnatm1.1Otin/Lmnatm1.1Otin
Nat10tm1a(KOMP)Wtsi/Nat10+
involves: 129P2/OlaHsd * C57BL/6NTac 		decreased heart rate J:261974
kyphosis J:261974
premature death J:261974
reduced fertility J:261974
normal reproductive system phenotype J:261974
normal vision/eye phenotype J:261974
Lmnatm1Stw/Lmna+
Zmpste24tm1Sgy/Zmpste24tm1Sgy
involves: 129S1/Sv * 129S4/SvJae * C57BL/6 		normal cellular phenotype J:95274
normal growth/size/body region phenotype J:95274
normal muscle phenotype J:95274
normal skeleton phenotype J:95274
Lmnatm1Stw/Lmna+
Mliptm1.1(cre)Dzw/Mliptm1.1(cre)Dzw
involves: 129S1/Sv * C57BL/6 		decreased cardiac muscle contractility J:227485
dilated cardiomyopathy J:227485
dilated heart left ventricle J:227485
Lmnatm1Stw/Lmnatm1Stw
Mliptm1.1(cre)Dzw/Mlip+
involves: 129S1/Sv * C57BL/6 		premature death J:227485
Lmnatm1Stw/Lmnatm1Stw
Mliptm1.1(cre)Dzw/Mliptm1.1(cre)Dzw
involves: 129S1/Sv * C57BL/6 		decreased cardiac muscle contractility J:227485
dilated heart left ventricle J:227485
premature death J:227485
Lmnatm1Stw/Lmnatm1Stw
Slnem1Cyh/Slnem1Cyh
involves: 129S1/Sv * C57BL/6J 		decreased body weight J:284048
premature death J:284048
Lmnatm1Stw/Lmnatm1Stw
Zmpste24tm1Sgy/Zmpste24+
involves: 129S1/Sv * 129S4/SvJae * C57BL/6 		muscle weakness J:95274
postnatal growth retardation J:95274
premature death J:95274
Lmnatm1Stw/Lmnatm1Stw
Zmpste24tm1Sgy/Zmpste24tm1Sgy
involves: 129S1/Sv * 129S4/SvJae * C57BL/6 		muscle weakness J:95274
postnatal growth retardation J:95274
premature death J:95274
Lmnatm2Lgf/Lmna+
Zmpste24tm1Sgy/Zmpste24tm1Sgy
involves: 129S4/SvJae * C57BL/6 		normal cellular phenotype J:106473
normal growth/size/body region phenotype J:106473
normal muscle phenotype J:106473
normal skeleton phenotype J:106473
Lmnatm6Lgf/Lmna+
Zmpste24tm1Sgy/Zmpste24tm1Sgy
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		decreased body weight J:160705
decreased survivor rate J:160705
premature death J:160705
Lmnatm6Lgf/Lmnatm6Lgf
Zmpste24tm1Sgy/Zmpste24tm1Sgy
involves: 129P2/OlaHsd * 129S4/SvJae 		normal digestive/alimentary phenotype J:220988
Lmnatm6Lgf/Lmnatm6Lgf
Zmpste24tm1Sgy/Zmpste24tm1Sgy
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		decreased body weight J:160705
decreased survivor rate J:160705
premature death J:160705
Lmnatm7Lgf/Lmna+
Zmpste24tm1Sgy/Zmpste24tm1Sgy
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		decreased susceptibility to bone fracture J:165928
normal growth/size/body region phenotype J:165928
normal mortality/aging J:165928
Lmnatm10Lgf/Lmnatm10Lgf
Zmpste24tm1Sgy/Zmpste24tm1Sgy
involves: 129P2/OlaHsd * 129S4/SvJae 		abnormal colon morphology J:220988
abnormal esophageal squamous epithelium morphology J:220988
dilated esophagus J:220988
distended cecum J:220988
esophageal achalasia J:220988
normal nervous system phenotype J:220988
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory