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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
L1cam
L1 cell adhesion molecule
MGI:96721
59 phenotypes from 9 alleles in 13 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
L1camtm1(tTA)Msch/L1cam+
129.Cg-L1camtm1(tTA)Msch
abnormal behavioral response to light J:227318
abnormal social investigation J:227318
normal behavior/neurological phenotype J:227318
increased grooming behavior J:227318
L1camtm1(tTA)Msch/Y
involves: 129 * C57BL/6J
abnormal brain ventricle morphology J:107878
abnormal cerebral aqueduct morphology J:107878
abnormal hippocampus morphology J:107878
cerebellum atrophy J:107878
decreased body size J:107878
enlarged cranium J:107878
hydrocephaly J:107878
thin cerebral cortex J:107878
L1camtm1.1Pfm/Y
Not Specified
abnormal axon guidance J:131051
abnormal retina ganglion cell morphology J:131051
normal nervous system phenotype J:131051
L1camtm1.1Pfm/L1camtm1.1Pfm
Not Specified
abnormal axon guidance J:131051
abnormal axon morphology J:131051
abnormal retina ganglion cell morphology J:131051
normal nervous system phenotype J:131051
L1camtm1.1Vlem/L1camtm1.1Vlem
129S2.Cg-L1camtm1.1Vlem
normal nervous system phenotype J:89300
prenatal lethality, incomplete penetrance J:89300
L1camtm1.1Vlem/L1camtm1.1Vlem
B6.Cg-L1camtm1.1Vlem
hydrocephaly J:89300
postnatal lethality, complete penetrance J:89300
prenatal lethality, incomplete penetrance J:89300
L1camtm1Fmo/Y
Tg(Camk2a-cre)1Gsc/0
involves: 129/Sv * C57BL/6
abnormal CNS synaptic transmission J:86626
abnormal spatial learning J:86626
decreased anxiety-related response J:86626
hyperactivity J:86626
increased exploration in new environment J:86626
increased vertical activity J:86626
L1camtm1Mtei/Y
either: (involves: 129/Sv * C57BL/6J) or (involves: 129/Sv * 129S/SvEv)
abnormal motor capabilities/coordination/movement J:43838
abnormal neuron morphology J:43838
abnormal response to tactile stimuli J:43838
abnormal Schwann cell morphology J:43838
abnormal thermal nociception J:43838
decreased body size J:43838
decreased corticospinal tract size J:43838
decreased grip strength J:43838
enlarged brain ventricles J:43838
enophthalmos J:43838
impaired limb coordination J:43838
L1camtm1Mtei/Y
involves: 129
normal nervous system phenotype J:136656
L1camtm1Mtei/Y
involves: 129 * C57BL/6J
abnormal cerebral aqueduct morphology J:107878
abnormal hippocampus morphology J:107878
cerebellum atrophy J:107878
decreased body size J:107878
enlarged brain ventricles J:107878
enlarged cranium J:107878
hydrocephaly J:107878
thin cerebral cortex J:107878
L1camtm1Sor/Y
either: 129S7/SvEvBrd-L1camtm1Sor or (129S7/SvEvBrd * C57BL/6J)F1
abnormal axon guidance J:45013
abnormal coat/hair pigmentation J:45013
abnormal corticospinal tract morphology J:45013
abnormal motor capabilities/coordination/movement J:45013
decreased body size J:45013
enophthalmos J:45013
excessive tearing J:45013
hindlimb paralysis J:45013
long toenails J:45013
male infertility J:45013
normal mortality/aging J:45013
normal nervous system phenotype J:45013
prenatal lethality, incomplete penetrance J:45013
normal reproductive system phenotype J:45013
slow postnatal weight gain J:45013
L1camtm1Sor/Y
involves: 129S7/SvEvBrd
abnormal axon extension J:47995
abnormal brain morphology J:47995
abnormal cerebellum morphology J:47995
abnormal cerebral aqueduct morphology J:47995
abnormal fourth ventricle morphology J:47995
abnormal sensory neuron innervation pattern J:137627
abnormal social/conspecific interaction behavior J:47995
abnormal somatic nervous system physiology J:137627
abnormal spatial learning J:47995
abnormal spinal cord dorsal horn morphology J:137627
cerebellum vermis hypoplasia J:47995
decreased body weight J:47995
decreased locomotor activity J:47995
dilated lateral ventricle J:47995
enlarged fourth ventricle J:47995
impaired coordination J:47995
increased thigmotaxis J:47995
L1camtm2.1Vlem/Y
either: 129S4.129S2-L1camtm2.1Vlem or B6.129S4-L1camtm2.1Vlem
normal behavior/neurological phenotype J:197240
normal mortality/aging J:197240
normal nervous system phenotype J:197240
L1camtm3.1Vlem/Y
either: 129S4.129S2-L1camtm3.1Vlem or B6.129S4-L1camtm3.1Vlem
abnormal neurite morphology J:197240
normal behavior/neurological phenotype J:197240
impaired coordination J:197240
normal mortality/aging J:197240
normal nervous system phenotype J:197240
L1camtm4.1Vlem/Y
either: 129S4.129S2-L1camtm4.1Vlem or B6.129S4-L1camtm4.1Vlem
abnormal neurite morphology J:197240
normal behavior/neurological phenotype J:197240
impaired coordination J:197240
normal mortality/aging J:197240
normal nervous system phenotype J:197240

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory