45 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Airetm1.1Doi/Airetm1.1Doi Il1r1tm1Imx/Il1r1+ involves: 129S2/SvPas * 129S7/SvEvBrd * NOD	abnormal conjunctiva goblet cell morphology	J:163691
	abnormal corneal epithelium morphology	J:163691
	abnormal lacrimal gland morphology	J:163691
	abnormal ocular surface morphology	J:163691
	corneal opacity	J:163691
	dry eyes	J:163691
	keratoconjunctivitis	J:163691
	lacrimal gland inflammation	J:163691
Airetm1.1Doi/Airetm1.1Doi Il1r1tm1Imx/Il1r1tm1Imx involves: 129S2/SvPas * 129S7/SvEvBrd * NOD	abnormal conjunctiva goblet cell morphology	J:163691
	abnormal corneal epithelium morphology	J:163691
	corneal opacity	J:163691
	dry eyes	J:163691
	keratoconjunctivitis	J:163691
	lacrimal gland inflammation	J:163691
Apoetm1Unc/Apoetm1Unc Il1r1tm1Imx/Il1r1tm1Imx B6.129-Il1r1tm1Imx Apoetm1Unc	abnormal blood vessel physiology	J:148173
	decreased circulating interleukin-6 level	J:148173
	decreased susceptibility to atherosclerosis	J:148173
	decreased systemic arterial blood pressure	J:148173
	increased vasoconstriction	J:148173
	increased vasodilation	J:148173
Casp1tm1Flv/Casp1tm1Flv Casp4del/Casp4del Il1r1tm1Imx/Il1r1tm1Imx involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6	decreased susceptibility to endotoxin shock	J:43088
Il1r1tm1Imx/Il1r1tm1Imx Tnfrsf1atm1Imx/Tnfrsf1atm1Imx involves: 129S7/SvEvBrd * C57BL/6	abnormal chemokine level	J:126652
	decreased interleukin-6 secretion	J:115094
	decreased susceptibility to experimental autoimmune uveoretinitis	J:115094
	dental pulp necrosis	J:58851
	impaired neutrophil recruitment	J:126652
	increased bone resorption	J:58851
	increased susceptibility to bacterial infection	J:58851
	interstitial pneumonia	J:126652
	lung inflammation	J:126652
	osteomyelitis	J:58851
Il1r1tm1Imx/Il1r1tm1Imx Vsig4tm1Gne/Vsig4tm1Gne B6.Cg-Il1r1tm1Imx Vsig4tm1Gne	decreased susceptibility to experimental autoimmune encephalomyelitis	J:281762
	decreased T helper 1 cell number	J:281762
	decreased T-helper 17 cell number	J:281762
	increased susceptibility to induced colitis	J:281762
Il1r1tm1Roml/Il1r1tm1Roml Mefvtm5.1(MEFV)Chae/Mefvtm5.1(MEFV)Chae involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6	normal immune system phenotype	J:172117
	increased interleukin-1 beta secretion	J:172117
Il1r1tm1Roml/Il1r1tm1Roml Nlrp1aNeut1/Nlrp1aNeut1 involves: 129S1/Sv * C57BL/6	abnormal leukocyte cell number	J:191055
	abnormal leukopoiesis	J:191055
	decreased eosinophil cell number	J:191055
	decreased lymphocyte cell number	J:191055
	decreased monocyte cell number	J:191055
	normal immune system phenotype	J:191055
	increased susceptibility to Riboviria infection	J:191055
	increased susceptibility to xenobiotic induced morbidity/mortality	J:191055
	thrombocytopenia	J:191055
Il1r1tm1Roml/Il1r1tm1Roml Nlrp3tm1Hhf/Nlrp3+ Lyz2tm1(cre)Ifo/Lyz2+ involves: 129 * C57BL/6	normal mortality/aging	J:150054
	skin inflammation	J:150054
Il1r1tm1Roml/Il1r1tm1Roml Tg(KRT14-Il1f6)1Hblu/? involves: 129S1/Sv * C57BL/6 * DBA/2	abnormal skin morphology	J:126327
Tnfrsf1atm1Imx/Tnfrsf1atm1Imx Il1r1tm1Imx/Il1r1tm1Imx B6;129S-Tnfrsf1atm1Imx Il1r1tm1Imx/J	abnormal brain wave pattern	J:137505
	abnormal circadian temperature homeostasis	J:137505
	abnormal sleep pattern	J:137505