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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Igf2
insulin-like growth factor 2
MGI:96434
68 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Apobtm2Sgy/Apobtm2Sgy
Ldlrtm1Her/Ldlrtm1Her
Tg(Ins-Igf2)1Fbos/?
involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL 		abnormal aorta bulb morphology J:227165
abnormal aortic valve morphology J:227165
abnormal cardiovascular system physiology J:227165
abnormal fasting circulating glucose level J:227165
abnormal heart left ventricle morphology J:227165
abnormal heart ventricles weight J:227165
aortic valve stenosis J:227165
aortitis J:227165
calcified aortic valve J:227165
cardiac fibrosis J:227165
cardiac hypertrophy J:227165
decreased cardiac muscle contractility J:227165
heart left ventricle hypertrophy J:227165
increased cardiac output J:227165
increased cardiac stroke volume J:227165
increased circulating cholesterol level J:227165
increased circulating insulin level J:227165
small aortic valve J:227165
Apobtm2Sgy/Apobtm2Sgy
Ldlrtm1Her/Ldlrtm1Her
Tg(Ins-Igf2)1Fbos/?
involves: 129S7/SvEvBrd * C57BL/6 * SJL 		atherosclerotic lesions J:141333
impaired glucose tolerance J:141333
increased circulating glucose level J:141333
increased circulating insulin level J:141333
Gpc3tm1Arge/Gpc3+
Igf2tm1Rob/Igf2+
involves: 129S/SvEv * 129S1/Sv * C57BL/6J 		abnormal body size J:75054
maternal imprinting J:75054
Gpc3tm1Arge/Y
Igf2tm1Rob/Igf2+
involves: 129S/SvEv * 129S1/Sv * C57BL/6J 		abnormal body size J:75054
maternal imprinting J:75054
H19tm1Tilg/H19+
Igf2tm1Rob/Igf2+
involves: 129S/SvEv 		normal growth/size/body region phenotype J:25091
Igf1tm1Arge/Igf1tm1Arge
Igf2tm1Rob/Igf2+
either: (involves: 129S/SvEv) or (involves: 129S/SvEv * C57BL/6J) or (involves: 129S/SvEv * MF1) 		decreased birth weight J:15108
delayed bone ossification J:15108
maternal imprinting J:15108
neonatal lethality, complete penetrance J:15108
respiratory failure J:15108
thin epidermis stratum spinosum J:15108
Igf1rtm1Arge/Igf1rtm1Arge
Igf2tm1Rob/Igf2+
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
small placenta J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2tm1Rob/Igf2+
involves: 129S/SvEv 		abnormal epidermal layer morphology J:15108
abnormal nervous system morphology J:15108
decreased birth weight J:15108
delayed bone ossification J:15108
maternal imprinting J:15108
neonatal lethality, complete penetrance J:15108
respiratory failure J:15108
Igf1rtm1Arge/Igf1rtm1Arge
Igf2tm1Rob/Igf2+
Igf2rtm1Arge/Igf2r+
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
small placenta J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2tm1Rob/Igf2+
Igf2rtm1Arge/Igf2rtm1Arge
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
small placenta J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2tm1Rob/Igf2+
Igf2rtm2Arge/Igf2r+
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
small placenta J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2tm1Rob/Igf2+
Igf2rtm2Arge/Igf2rtm2Arge
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
small placenta J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2tm1Rob/Igf2tm1Rob
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
small placenta J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2tm1Rob/Igf2tm1Rob
Igf2rtm1Arge/Igf2r+
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
small placenta J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2tm1Rob/Igf2tm1Rob
Igf2rtm1Arge/Igf2rtm1Arge
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
small placenta J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2tm1Rob/Igf2tm1Rob
Igf2rtm2Arge/Igf2rtm2Arge
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
small placenta J:34584
Igf2tm1Kel/Igf2+
Phlda2tm1Bty/Phlda2+
involves: 129/Sv * C57BL/6 		decreased fetal weight J:76871
decreased placenta weight J:76871
increased spongiotrophoblast size J:76871
Igf2tm1Kel/Igf2+
Phlda2tm2Bty/Phlda2+
involves: 129/Sv * C57BL/6 		decreased fetal weight J:76871
decreased placenta weight J:76871
increased spongiotrophoblast size J:76871
Igf2tm1Rob/Igf2+
Igf2rtm1Arge/Igf2r+
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
increased birth weight J:34584
small placenta J:34584
Igf2tm1Rob/Igf2+
Igf2rtm1Arge/Igf2r+
M6prtm1Hlk/M6pr+
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased body size J:34584
normal mortality/aging J:34584
normal reproductive system phenotype J:34584
Igf2tm1Rob/Igf2+
Igf2rtm1Arge/Igf2r+
M6prtm1Hlk/M6prtm1Hlk
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		abnormal gait J:34584
decreased body size J:34584
postnatal lethality, complete penetrance J:34584
Igf2tm1Rob/Igf2+
Igf2rtm1Arge/Igf2rtm1Arge
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
increased birth weight J:34584
small placenta J:34584
Igf2tm1Rob/Igf2+
Igf2rtm2Arge/Igf2r+
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
increased birth weight J:34584
small placenta J:34584
Igf2tm1Rob/Igf2+
Igf2rtm2Arge/Igf2r+
M6prtm1Hlk/M6pr+
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased body size J:34584
normal mortality/aging J:34584
normal reproductive system phenotype J:34584
Igf2tm1Rob/Igf2+
Igf2rtm2Arge/Igf2r+
M6prtm1Hlk/M6prtm1Hlk
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		abnormal gait J:34584
decreased body size J:34584
postnatal lethality, complete penetrance J:34584
Igf2tm1Rob/Igf2+
Igf2rtm2Arge/Igf2rtm2Arge
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
increased birth weight J:34584
small placenta J:34584
Igf2tm1Rob/Igf2+
M6prtm1Hlk/M6pr+
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased body size J:34584
Igf2tm1Rob/Igf2+
M6prtm1Hlk/M6prtm1Hlk
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased body size J:34584
Igf2tm1Rob/Igf2tm1Rob
Igf2rtm1.1(IGF2R)Arte/Igf2r+
involves: C57BL/6J * C57BL/6NTac 		normal growth/size/body region phenotype J:197171
normal mortality/aging J:197171
Igf2tm1Rob/Igf2tm1Rob
Igf2rtm1Arge/Igf2r+
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
small placenta J:34584
Igf2tm1Rob/Igf2tm1Rob
Igf2rtm1Arge/Igf2r+
M6prtm1Hlk/M6pr+
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased body size J:34584
normal mortality/aging J:34584
normal reproductive system phenotype J:34584
Igf2tm1Rob/Igf2tm1Rob
Igf2rtm1Arge/Igf2r+
M6prtm1Hlk/M6prtm1Hlk
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		abnormal gait J:34584
decreased body size J:34584
postnatal lethality, complete penetrance J:34584
Igf2tm1Rob/Igf2tm1Rob
Igf2rtm1Arge/Igf2rtm1Arge
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
small placenta J:34584
Igf2tm1Rob/Igf2tm1Rob
Igf2rtm2Arge/Igf2r+
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
small placenta J:34584
Igf2tm1Rob/Igf2tm1Rob
Igf2rtm2Arge/Igf2r+
M6prtm1Hlk/M6pr+
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased body size J:34584
normal mortality/aging J:34584
normal reproductive system phenotype J:34584
Igf2tm1Rob/Igf2tm1Rob
Igf2rtm2Arge/Igf2r+
M6prtm1Hlk/M6prtm1Hlk
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		abnormal gait J:34584
decreased body size J:34584
postnatal lethality, complete penetrance J:34584
Igf2tm1Rob/Igf2tm1Rob
Igf2rtm2Arge/Igf2rtm2Arge
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
small placenta J:34584
Igf2tm1Rob/Igf2tm1Rob
M6prtm1Hlk/M6pr+
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased body size J:34584
Igf2tm1Rob/Igf2tm1Rob
M6prtm1Hlk/M6prtm1Hlk
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased body size J:34584
Rr28tm1Tilg/Rr28+
Igf2tm1Rob/Igf2+
involves: 129S/SvEv * 129S1/Sv * C57BL/6J 		abnormal circulating hormone level J:77413
abnormal fetal cardiomyocyte proliferation J:77413
abnormal heart septum morphology J:77413
abnormal heart ventricle morphology J:77413
abnormal lens development J:77413
abnormal lens epithelium morphology J:77413
abnormal lumbar vertebrae morphology J:77413
abnormal myocardium layer morphology J:77413
adrenal gland cyst J:77413
cleft palate J:77413
decreased kidney weight J:77413
delayed eyelid fusion J:77413
edema J:77413
enlarged aortic valve J:77413
enlarged pulmonary valve J:77413
increased fetal weight J:77413
increased heart weight J:77413
increased hepatocyte proliferation J:77413
increased liver weight J:77413
increased placenta weight J:77413
lethality throughout fetal growth and development, complete penetrance J:77413
omphalocele J:77413
pericardial edema J:77413
polydactyly J:77413
split sternum J:77413
thick aortic valve J:77413
thick pulmonary valve J:77413
Rr28tm1Tilg/Rr28+
Igf2tm1Rob/Igf2+
Igf2rtm1Stw/Igf2r+
involves: 129S/SvEv * 129S1/Sv * C57BL/6J 		increased fetal weight J:77413
neonatal lethality, complete penetrance J:77413
polydactyly J:77413
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory