90 phenotypes from 8 alleles in 16 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Igf1rhyft/Igf1rhyft Not Specified	abnormal liver morphology	J:75360
	hydrops fetalis	J:75360
Igf1rtm1.1Mhz/Igf1rtm1.1Mhz involves: 129/Sv * C57BL/6 * FVB/N	normal growth/size/body region phenotype	J:63460
Igf1rtm1.1Mhz/Igf1rtm1.1Mhz Tg(Ckmm-cre)5Khn/0 involves: 129/Sv * C57BL/6 * FVB	normal growth/size/body region phenotype	J:118987
	normal homeostasis/metabolism phenotype	J:118987
	increased heart weight	J:118987
Igf1rtm1.1Mhz/Igf1rtm1.1Mhz Tg(Ins2-cre)25Mgn/0 involves: 129/Sv * C57BL/6 * DBA/2	normal digestive/alimentary phenotype	J:121640
	hyperglycemia	J:121640
	impaired glucose tolerance	J:121640
	normal mortality/aging	J:121640
Igf1rtm1.2Mhz/Igf1rtm1.2Mhz involves: 129/Sv * C57BL/6 * FVB/N	abnormal muscle morphology	J:63460
	decreased body weight	J:63460
	neonatal lethality, complete penetrance	J:63460
	respiratory failure	J:63460
Igf1rtm1Arge/Igf1r+ involves: 129S/SvEv	abnormal postnatal growth/weight/body size	J:15108
Igf1rtm1Arge/Igf1rtm1Arge involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
Igf1rtm1Arge/Igf1rtm1Arge involves: 129/Sv * 129S/SvEv	decreased birth weight	J:34584
Igf1rtm1Arge/Igf1rtm1Arge involves: 129S/SvEv	abnormal brainstem morphology	J:15108
	abnormal hair follicle morphology	J:15108
	abnormal spinal cord morphology	J:15108
	atelectasis	J:15108
	cyanosis	J:15108
	decreased birth weight	J:15108
	decreased hair follicle number	J:15108
	decreased oligodendrocyte progenitor number	J:15108
	delayed bone ossification	J:15108
	muscle hypoplasia	J:15108
	neonatal lethality, complete penetrance	J:15108
	respiratory failure	J:15108
	small hair follicles	J:15108
	thin epidermis	J:15108
	thin epidermis stratum spinosum	J:15108
	translucent skin	J:15108
Igf1rtm1Arge/Igf1rtm2Arge Tg(Camk2a-cre)2Szi/0 involves: 129S/SvEv * C57BL/6J * CBA	abnormal CNS glial cell morphology	J:88198
	abnormal myelination	J:88198
	abnormal oligodendrocyte morphology	J:88198
	decreased oligodendrocyte progenitor number	J:88198
Igf1rtm1Jcbr/Igf1rtm1Jcbr Ndor1Tg(UBC-cre/ERT2)1Ejb/0 B6.Cg-Ndor1Tg(UBC-cre/ERT2)1Ejb Igf1rtm1Jcbr	abnormal susceptibility to injury induced morbidity/mortality	J:241920
	decreased airway responsiveness	J:241924
	decreased collagen level	J:241924
	decreased respiratory mucosa goblet cell number	J:241924
	decreased susceptibility to injury	J:241920
	decreased susceptibility to type I hypersensitivity reaction	J:241924
Igf1rtm1Jcbr/Igf1rtm1Jcbr Ndor1Tg(UBC-cre/ERT2)1Ejb/0 involves: 129S/SvEv * C57BL/6	abnormal bronchiole epithelium morphology	J:221618
	abnormal pulmonary alveolar parenchyma morphology	J:221618
	abnormal spermatogenesis	J:221618
	azoospermia	J:221618
	decreased body weight	J:221618
	decreased testis weight	J:221618
	increased hepatocyte proliferation	J:221618
	oligozoospermia	J:221618
	postnatal growth retardation	J:221618
	normal reproductive system phenotype	J:221618
	small seminiferous tubules	J:221618
Igf1rtm1Jcbr/Igf1rtm1Jcbr Tg(Fabp4-cre)1Abel/? involves: C57BL/6 * FVB/N	abnormal fat cell morphology	J:141321
	abnormal glucose homeostasis	J:141321
	abnormal gonadal fat pad morphology	J:141321
	decreased adiponectin level	J:141321
	decreased brain size	J:141321
	increased body length	J:141321
	increased body weight	J:141321
	increased circulating glucose level	J:141321
	increased fat cell size	J:141321
	increased heart weight	J:141321
	increased insulin sensitivity	J:141321
	increased liver weight	J:141321
	increased total body fat amount	J:141321
Igf1rtm1Jcbr/Igf1rtm1Jcbr Tg(Nkx2-1-cre)2Sand/0 involves: C57BL/6	abnormal bronchiole epithelium morphology	J:241923
	abnormal response to injury	J:241923
	increased body weight	J:241923
Igf1rtm1Jcbr/Igf1rtm1Jcbr Tg(Scgb1a1-cre)1Tauc/0 involves: C57BL/6	abnormal bronchiole epithelium morphology	J:241923
	abnormal response to injury	J:241923
Igf1rtm1Mhz/Igf1rtm1Mhz involves: 129/Sv * C57BL/6	decreased body weight	J:63460
	normal homeostasis/metabolism phenotype	J:63460
	postnatal growth retardation	J:63460
Igf1rtm2.1Arge/Igf1rtm2.1Arge involves: 129 * C57BL/6	abnormal bony labyrinth	J:178908
	abnormal cochlea morphology	J:178908
	abnormal cochlear hair cell development	J:178908
	abnormal cochlear hair cell stereociliary bundle morphology	J:178908
	abnormal cochlear inner hair cell morphology	J:178908
	abnormal cochlear outer hair cell morphology	J:178908
	abnormal cochlear sensory epithelium morphology	J:178908
	abnormal inner hair cell kinocilium morphology	J:178908
	abnormal lateral semicircular canal morphology	J:178908
	abnormal posterior semicircular canal morphology	J:178908
	abnormal semicircular canal morphology	J:178908
	decreased cochlear hair cell number	J:178908
	decreased cochlear inner hair cell number	J:178908
	decreased cochlear outer hair cell number	J:178908
	neonatal lethality, complete penetrance	J:178908
	prenatal growth retardation	J:178908
	respiratory failure	J:178908
Igf1rtm2Arge/Igf1r+ Tg(Tek-cre)1Ywa/0 B6.Cg-Tg(Tek-cre)1Ywa Igf1rtm2Arge	abnormal vascular endothelial cell physiology	J:208523
	abnormal vascular wound healing	J:208523
Igf1rtm2Arge/Igf1rtm2Arge Tg(BGLAP-cre)1Clem/0 involves: 129 * FVB/N	abnormal osteoblast physiology	J:80190
	abnormal osteoclast physiology	J:80190
	abnormal skeleton morphology	J:80190
	abnormal skeleton physiology	J:80190
	abnormal trabecular bone morphology	J:80190
	decreased bone mineralization	J:80190
	decreased bone ossification	J:80190
	decreased bone trabecula number	J:80190
	decreased osteoblast cell number	J:80190
	decreased osteoclast cell number	J:80190
	decreased trabecular bone thickness	J:80190
	decreased trabecular bone volume	J:80190
	thin neurocranium	J:80190