Gata4em1Vigr/Gata4em1Vigr
involves: C3H/HeJ * C57BL/6J
|
normal
reproductive system phenotype |
J:308912
|
Gata4Tg(Tyr)2265AOve/Gata4Tg(Tyr)2265AOve
FVB/N-Gata4Tg(Tyr)2265AOve
|
embryonic lethality between somite formation and embryo turning, complete penetrance |
J:175597
|
Gata4tm1(cre)Svs/Gata4+
Tg(Sox3-GFP,Tyr)HolNpln/Tg(Sox3-GFP,Tyr)HolNpln
involves: 129S1/Sv * 129X1/SvJ * FVB/N
|
abnormal enteric neural crest cell migration |
J:229828
|
|
decreased neuronal precursor cell number |
J:229828
|
Gata4tm1.1Jmol/Gata4tm1.1Jmol
involves: 129 * C57BL/6
|
abnormal heart ventricle morphology |
J:174537
|
|
abnormal response of heart to induced stress |
J:174537
|
|
decreased circulating testosterone level |
J:308912
|
|
decreased response of heart to induced stress |
J:174537
|
|
decreased seminal vesicle weight |
J:308912
|
Gata4tm1.1Sad/Gata4tm1.1Sad
Amhr2tm3(cre)Bhr/Amhr2+
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6J
|
abnormal circulating hormone level |
J:173711
|
|
abnormal ovary physiology |
J:173711
|
|
abnormal seminiferous tubule epithelium morphology |
J:169018
|
|
abnormal Sertoli cell barrier function |
J:169018
|
|
abnormal Sertoli cell morphology |
J:169018
|
|
abnormal spermatid morphology |
J:169018
|
|
abnormal spermatogenesis |
J:169018
|
|
asthenozoospermia |
J:169018
|
|
decreased litter size |
J:173711
|
|
decreased male germ cell number |
J:169018
|
|
decreased sperm progressive motility |
J:169018
|
|
decreased superovulation rate |
J:173711
|
|
decreased testis weight |
J:169018
|
|
failure of superovulation |
J:173711
|
|
female infertility |
J:173711
|
|
normal
homeostasis/metabolism phenotype |
J:169018
|
|
increased male germ cell apoptosis |
J:169018
|
|
multinucleated giant male germ cells |
J:169018
|
|
oligozoospermia |
J:169018
|
|
ovarian follicular cyst |
J:173711
|
|
ovary cyst |
J:173711
|
|
reduced female fertility |
J:173711
|
|
reduced male fertility |
J:169018
|
|
normal
reproductive system phenotype |
J:169018,
J:173711
|
|
seminiferous tubule degeneration |
J:169018
|
|
small ovary |
J:173711
|
|
small testis |
J:169018
|
|
testicular atrophy |
J:169018
|
Gata4tm1.1Sad/Gata4tm1.1Sad
Nkx2-5tm1(cre)Rjs/Nkx2-5+
involves: 129S1/Sv * 129X1/SvJ * CD-1
|
increased cardiomyocyte apoptosis |
J:121367
|
|
prenatal lethality, complete penetrance |
J:121367
|
|
thin ventricular wall |
J:121367
|
Gata4tm1.1Sad/Gata4tm1.1Sad
Tg(Myh6-cre)1Jmk/0
involves: 129S1/Sv * 129X1/SvJ * CD-1
|
abnormal myocardial fiber morphology |
J:121367
|
|
decreased cardiac muscle contractility |
J:121367
|
|
dilated heart |
J:121367
|
|
pulmonary edema |
J:121367
|
Gata4tm1.1Sad/Gata4tm1.1Sad
Tg(Myh7-cre)1Jmk/0
involves: 129S1/Sv * 129X1/SvJ * CD-1
|
abnormal heart ventricle morphology |
J:121367
|
|
abnormal myocardial fiber morphology |
J:121367
|
|
cardiac hypertrophy |
J:121367
|
|
decreased cardiac muscle contractility |
J:121367
|
|
dilated heart |
J:121367
|
|
dilated heart left ventricle |
J:121367
|
|
increased cardiomyocyte apoptosis |
J:121367
|
|
premature death |
J:121367
|
|
pulmonary edema |
J:121367
|
Gata4tm1.1Sad/Gata4tm1.1Sad
Tg(Tek-cre)1Ywa/?
involves: 129S1/Sv * 129X1/SvJ * CD-1
|
normal
cardiovascular system phenotype |
J:92434
|
Gata4tm1.1Sad/Gata4tm1.2Sad
Pax3tm1(cre)Joe/Pax3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
|
normal
muscle phenotype |
J:231793
|
Gata4tm1.1Sad/Gata4tm1.2Sad
Tg(Prrx1-cre)1Cjt/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J
|
abnormal diaphragm development |
J:231793
|
|
abnormal lung lobe morphology |
J:231793
|
|
abnormal lung volume |
J:231793
|
|
abnormal muscle precursor cell morphology |
J:231793
|
|
abnormal muscle precursor cell physiology |
J:231793
|
|
decreased blood oxygen saturation level |
J:231793
|
|
diaphragmatic hernia |
J:231793
|
|
neonatal lethality |
J:231793
|
Gata4tm1.1Sho/Gata4tm1.1Sho
involves: 129S6/SvEvTac
|
abnormal cardiovascular system morphology |
J:77392
|
|
embryonic lethality during organogenesis, complete penetrance |
J:77392
|
Gata4tm1.1Wtp/Gata4tm1.1Wtp
Nkx2-5tm1(cre)Rjs/Nkx2-5+
involves: 129S7/SvEvBrd
|
abnormal cardiac epithelial to mesenchymal transition |
J:99203
|
|
abnormal fetal cardiomyocyte proliferation |
J:99203
|
|
atrioventricular cushion hypoplasia |
J:99203
|
|
common ventricle |
J:99203
|
|
conotruncal ridge hypoplasia |
J:99203
|
|
embryonic growth retardation |
J:99203
|
|
heart hypoplasia |
J:99203
|
|
heart right ventricle hypoplasia |
J:99203
|
|
lethality throughout fetal growth and development, complete penetrance |
J:99203
|
|
pericardial effusion |
J:99203
|
Gata4tm1.1Wtp/Gata4tm1.1Wtp
Tg(Myh6-cre)2182Mds/0
involves: FVB/N
|
abnormal fetal cardiomyocyte proliferation |
J:99203
|
|
double outlet right ventricle |
J:99203
|
|
heart hypoplasia |
J:99203
|
|
lethality throughout fetal growth and development, complete penetrance |
J:99203
|
Gata4tm1.2Wtp/Gata4+
B6.Cg-Gata4tm1.2Wtp
|
abnormal diaphragm central tendon morphology |
J:117367
|
|
abnormal endometrium morphology |
J:173711
|
|
abnormal heart morphology |
J:117367
|
|
abnormal lung morphology |
J:117367
|
|
abnormal lung saccule morphology |
J:117367
|
|
abnormal lung vasculature morphology |
J:117367
|
|
abnormal ovary physiology |
J:173711
|
|
atrioventricular septal defect |
J:117367
|
|
decreased circulating estradiol level |
J:173711
|
|
decreased ovary weight |
J:173711
|
|
decreased superovulation rate |
J:173711
|
|
decreased uterus weight |
J:173711
|
|
delayed estrous cycle |
J:173711
|
|
delayed sexual maturation |
J:173711
|
|
diaphragmatic hernia |
J:117367
|
|
dilated respiratory conducting tube |
J:117367
|
|
increased apoptosis |
J:117367
|
|
neonatal lethality, incomplete penetrance |
J:117367
|
|
normal
reproductive system phenotype |
J:173711
|
|
small ovary |
J:173711
|
|
ventricular septal defect |
J:117367
|
Gata4tm1.2Wtp/Gata4tm1.2Wtp
involves: 129 * C57BL/6
|
abnormal dorsal-ventral axis patterning |
J:94637
|
|
lethality throughout fetal growth and development, complete penetrance |
J:94637
|
Gata4tm1Eno/Gata4+
B6.129S7-Gata4tm1Eno
|
diaphragmatic hernia |
J:187416
|
Gata4tm1Eno/Gata4tm1Eno
involves: 129S7/SvEvBrd * C57BL/6
|
abnormal developmental patterning |
J:40145
|
|
abnormal dorsal-ventral axis patterning |
J:40145
|
|
abnormal extraembryonic coelom morphology |
J:40145
|
|
abnormal heart development |
J:40145
|
|
abnormal heart tube morphology |
J:40145
|
|
abnormal neural tube morphology |
J:40145
|
|
absent foregut |
J:40145
|
|
cardia bifida |
J:40145
|
|
decreased embryo size |
J:40145
|
|
embryonic growth arrest |
J:40145
|
|
embryonic growth retardation |
J:40145
|
|
embryonic lethality, complete penetrance |
J:40145
|
|
failure to gastrulate |
J:40145
|
Gata4tm1Grg/Gata4+
involves: 129 * C57BL/6
|
abnormal heart atrium morphology |
J:185124
|
|
aorta stenosis |
J:185124
|
|
atrial septal defect |
J:185124
|
|
decreased fetal cardiomyocyte proliferation |
J:185124
|
|
patent cardiac foramen ovale |
J:185124
|
|
pulmonary valve stenosis |
J:185124
|
|
thick aortic valve cusps |
J:185124
|
|
thick pulmonary valve cusps |
J:185124
|
|
thin ventricle myocardium compact layer |
J:185124
|
Gata4tm1Grg/Gata4tm1.1Wtp
Tg(Myh6-cre)2182Mds/0
involves: 129 * C57BL/6 * FVB/N
|
no abnormal phenotype detected |
J:185124
|
Gata4tm1Grg/Gata4tm1.1Wtp
Tg(Nkx2-5-cre)9Eno/0
involves: 129 * C57BL/6
|
embryonic growth retardation |
J:185124
|
|
embryonic lethality during organogenesis, incomplete penetrance |
J:185124
|
|
thin myocardium |
J:185124
|
Gata4tm1Grg/Gata4tm1.1Wtp
Tg(Tek-cre)1Ywa/0
involves: 129 * C57BL/6 * SJL
|
abnormal atrioventricular cushion morphology |
J:185124
|
|
normal
growth/size/body region phenotype |
J:185124
|
Gata4tm1Grg/Gata4tm1Grg
involves: 129 * C57BL/6
|
decreased fetal cardiomyocyte proliferation |
J:185124
|
|
delayed heart looping |
J:185124
|
|
embryonic growth retardation |
J:185124
|
|
embryonic lethality during organogenesis, complete penetrance |
J:185124
|
|
thin myocardium |
J:185124
|
|
thin ventricular wall |
J:185124
|
Gata4tm1Jml/Gata4tm1Jml
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1
|
abnormal dorsal-ventral axis patterning |
J:40144
|
|
abnormal foregut morphology |
J:40144
|
|
abnormal heart development |
J:40144
|
|
abnormal rostral-caudal axis patterning |
J:40144
|
|
abnormal visceral yolk sac morphology |
J:40144
|
|
absent heart tube |
J:40144
|
|
decreased embryo size |
J:40144
|
Gata4tm1Sho/Gata4+
C57BL/6JEi-Chr YA/HeJ/EiJ
|
primary sex reversal |
J:125196
|
|
true hermaphroditism |
J:125196
|
Gata4tm1Sho/Gata4+
Tg(Myh6-cre)2182Mds/0
involves: 129S6/SvEvTac
|
normal
cardiovascular system phenotype |
J:150452
|
Gata4tm1Sho/Gata4+
Nkx2-5tm1(cre)Rjs/Nkx2-5+
involves: 129S6/SvEvTac * 129S7/SvEvBrd
|
normal
cardiovascular system phenotype |
J:150452
|
Gata4tm1Sho/Gata4tm1.1Wtp
Nkx2-5tm1(cre)Rjs/Nkx2-5+
involves: 129S6/SvEvTac * 129S7/SvEvBrd
|
abnormal atrioventricular cushion morphology |
J:150452
|
|
abnormal coronary vessel morphology |
J:150452
|
|
hemorrhage |
J:150452
|
|
skin edema |
J:150452
|
|
thin myocardium compact layer |
J:150452
|
|
ventricular septal defect |
J:150452
|
Gata4tm1Sho/Gata4tm1.1Wtp
Tg(Myh6-cre)2182Mds/0
involves: 129S6/SvEvTac * 129S7/SvEvBrd
|
abnormal cardiovascular system physiology |
J:150452
|
|
dilated heart ventricle |
J:150452
|
Gata4tm1Sho/Gata4tm1Sho
involves: 129S6/SvEvTac
|
abnormal conotruncal ridge morphology |
J:77392
|
|
abnormal fetal Leydig cell differentiation |
J:78688
|
|
abnormal heart development |
J:77392
|
|
abnormal heart ventricle morphology |
J:77392
|
|
abnormal lung development |
J:134027
|
|
abnormal primary sex determination |
J:78688
|
|
abnormal Sertoli cell morphology |
J:78688
|
|
abnormal truncus arteriosus septation |
J:77392
|
|
absent coronary vessels |
J:77392
|
|
atrial septal defect |
J:77392
|
|
common atrioventricular valve |
J:77392
|
|
common ventricle |
J:77392
|
|
dilated heart atrium |
J:77392
|
|
double outlet right ventricle |
J:77392
|
|
edema |
J:77392
|
|
embryonic lethality during organogenesis, complete penetrance |
J:77392
|
|
hemorrhage |
J:77392
|
|
pallor |
J:77392
|
|
primary sex reversal |
J:78688
|
|
thin myocardium |
J:77392
|
|
ventricular septal defect |
J:77392
|
Gata4tm1Wtp/Gata4tm1Wtp
involves: 129 * C57BL/6
|
abnormal heart development |
J:94637
|
|
abnormal interventricular septum morphology |
J:94637
|
|
abnormal myocardium compact layer morphology |
J:94637
|
|
atrioventricular valve regurgitation |
J:94637
|
|
complete atrioventricular septal defect |
J:94637
|
|
decreased fetal cardiomyocyte proliferation |
J:94637
|
|
dilated heart right atrium |
J:94637
|
|
double outlet right ventricle |
J:94637
|
|
hydrops fetalis |
J:94637
|
|
lethality throughout fetal growth and development, complete penetrance |
J:94637
|
|
myocardial trabeculae hypoplasia |
J:94637
|
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