Ets2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ets2
E26 avian leukemia oncogene 2, 3' domain
MGI:95456

15 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ets1^tm1Jml/Ets1^tm1Jml Ets2^tm2Rgo/Ets2^tm2Rgo involves: 129S/SvEv * C57BL/6 * FVB/N	abnormal vascular branching morphogenesis	J:151187
	dilated vasculature	J:151187
	edema	J:151187
	normal embryo phenotype	J:151187
	embryonic lethality during organogenesis, incomplete penetrance	J:151187
	hemorrhage	J:151187
	increased vascular endothelial cell apoptosis	J:151187
	lethality throughout fetal growth and development, complete penetrance	J:151187
Ets1^tm1Jml/Ets1^tm1Jml Ets2^tm5.1Rgo/Ets2^tm5.1Rgo Meox2^tm1(cre)Sor/Meox2⁺ involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * FVB/N	edema	J:151187
	hemorrhage	J:151187
	prenatal lethality, complete penetrance	J:151187
Ets1^tm1Jml/Ets1^tm1Jml Ets2^tm5.1Rgo/Ets2^tm5.1Rgo Tg(Tek-cre)1Ywa/0 involves: 129S/SvEv * C57BL/6 * FVB/N	abnormal vascular branching morphogenesis	J:151187
	embryonic lethality, complete penetrance	J:151187
	increased vascular endothelial cell apoptosis	J:151187
Ets2^tm1Rgo/Ets2⁺ Tg(MMTV-PyVT)634Mul/0 involves: 129S2/SvPas * Black Swiss * FVB/N	decreased tumor growth/size	J:57272
Ets2^tm1Rgo/Ets2^tm5.1Rgo Pten^tm1.1Mwst/Pten^tm1.1Mwst Tg(S100a4-cre)1Gle/0 involves: 129S2/SvPas * FVB/N	abnormal tumor morphology	J:153747
	decreased mammary gland tumor incidence	J:153747
	increased mammary gland tumor incidence	J:153747
Ets2^tm1Rgo/Ets2^tm5.1Rgo Tg(MMTV-PyVT)634Mul/0 Tg(S100a4-cre)1Gle/0 involves: 129S2/SvPas * FVB/N	decreased mammary gland tumor incidence	J:153747
Ets2^tm3Rgo/Ets2⁺ Meox2^tm1(cre)Sor/? Tg(MMTV-PyVTY315FY322F)Db-1Mul/? involves: 129S4/SvJae * C57BL/6 * FVB/N	increased mammary gland tumor incidence	J:102368
Ets2^tm3Rgo/Ets2^tm3.1Rgo Meox2^tm1(cre)Sor/? Tg(MMTV-PyVTY315FY322F)Db-1Mul/? involves: 129S4/SvJae * C57BL/6 * FVB/N	increased mammary gland tumor incidence	J:102368
	mammary gland hyperplasia	J:102368

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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