86 phenotypes from 14 alleles in 16 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Egr2tm2(cre)Pch/Egr2+ Erbb2tm1Cbm/Erbb2tm2Cbm involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6	abnormal dorsal spinal root morphology	J:75421
	abnormal gait	J:75421
	abnormal locomotor activation	J:75421
	abnormal myelin sheath morphology	J:75421
	abnormal myelination	J:75421
	abnormal sciatic nerve morphology	J:75421
	abnormal ventral spinal root morphology	J:75421
	cachexia	J:75421
	decreased Schwann cell number	J:75421
	kinked tail	J:75421
	premature death	J:75421
Egr2tm2(cre)Pch/Egr2+ Erbb2tm2Cbm/Erbb2tm2Cbm involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6	normal behavior/neurological phenotype	J:199150
	demyelination	J:199150
Erbb2l11Jus8/Erbb2l11Jus8 129S5.B6(129S7)-Erbb2l11Jus8	abnormal atrium myocardium morphology	J:222460
	abnormal heart atrium morphology	J:222460
	abnormal vitelline vasculature morphology	J:222460
	absent vitelline blood vessels	J:222460
	atrioventricular block	J:222460
	normal cardiovascular system phenotype	J:222460
	dilated heart atrium	J:222460
	embryonic lethality during organogenesis, complete penetrance	J:222460
	hemorrhage	J:222460
Erbb2l11Jus8/Erbb2l11Jus8 Not Specified	abnormal blood circulation	J:85113
	embryonic lethality during organogenesis, complete penetrance	J:109155
	hemorrhage	J:85113
	kinked neural tube	J:85113
Erbb2tm1b(EUCOMM)Hmgu/Erbb2tm1b(EUCOMM)Hmgu C57BL/6N-Erbb2tm1b(EUCOMM)Hmgu/Ieg	preweaning lethality, complete penetrance	J:211773
Erbb2tm1Cbm/Erbb2+ involves: 129P2/OlaHsd	normal nervous system phenotype	J:90038
Erbb2tm1Cbm/Erbb2tm1Cbm involves: 129P2/OlaHsd * C57BL/6	abnormal cranial ganglia morphology	J:48515
	abnormal neural crest cell migration	J:48515
	abnormal sympathetic ganglion morphology	J:48515
	absent trabeculae carneae	J:48515
	decreased neuronal precursor cell number	J:48515
	decreased Schwann cell precursor number	J:48515
	embryonic lethality, complete penetrance	J:48515
Erbb2tm1Cbm/Erbb2tm2.1Cbm involves: 129P2/OlaHsd * C57BL/6	abnormal sympathetic ganglion morphology	J:75421
	absent trabeculae carneae	J:75421
	embryonic lethality, complete penetrance	J:75421
Erbb2tm1Cbm/Erbb2tm2Cbm Myl2tm1(cre)Krc/Myl2+ involves: 129P2/OlaHsd * 129S4/SvJae	abnormal myocardial fiber morphology	J:77347
	cardiac hypertrophy	J:77347
	decreased ventricle muscle contractility	J:77347
	dilated cardiomyopathy	J:77347
	increased heart ventricle size	J:77347
	postnatal lethality, incomplete penetrance	J:77347
	premature death	J:77347
	prolonged QT interval	J:77347
	thin ventricular wall	J:77347
Erbb2tm1Gne/Erbb2tm1Gne either: (involves: 129S2/SvPas * BALB/c) or (involves: 129S2/SvPas * C57BL/6J)	abnormal cochlear ganglion morphology	J:45302
	abnormal dorsal root ganglion morphology	J:45302
	abnormal geniculate ganglion morphology	J:45302
	abnormal glossopharyngeal nerve morphology	J:45302
	abnormal hypoglossal nerve morphology	J:45302
	abnormal petrosal ganglion morphology	J:45302
	abnormal trigeminal ganglion morphology	J:45302
	abnormal vagus nerve morphology	J:45302
	abnormal ventral spinal root morphology	J:45302
	absent myocardial trabeculae	J:45302
	embryonic lethality during organogenesis, complete penetrance	J:45302
	enlarged heart	J:45302
	irregular heartbeat	J:45302
	poor circulation	J:45302
	small superior vagus ganglion	J:45302
	thin ventricular wall	J:45302
Erbb2tm1Haus/Erbb2tm1Haus involves: 129S4/SvJae * C57BL/6	abnormal cranial ganglia morphology	J:29973
	abnormal cranial nerve morphology	J:29973
	abnormal geniculate ganglion morphology	J:29973
	abnormal glossopharyngeal nerve morphology	J:29973
	abnormal motor neuron innervation pattern	J:29973
	abnormal sensory neuron innervation pattern	J:29973
	abnormal trigeminal ganglion morphology	J:29973
	abnormal trigeminal nerve morphology	J:29973
	abnormal vagus nerve morphology	J:29973
	absent myocardial trabeculae	J:29973
	decreased atrioventricular cushion size	J:29973
	embryonic lethality, complete penetrance	J:29973
Erbb2tm1Haus/Erbb2tm1Klee Myf5tm3(cre)Sor/Myf5+ involves: 129S4/SvJae * C57BL/6	abnormal excitatory postsynaptic potential	J:147957
	abnormal gait	J:147957
	abnormal muscle spindle morphology	J:147957
	abnormal posture	J:147957
	abnormal sensory neuron innervation pattern	J:147957
	ataxia	J:147957
	decreased muscle spindle number	J:147957
Erbb2tm1Klee/Erbb2tm1Klee Myl2tm1(cre)Krc/Myl2+ involves: 129S4/SvJae	abnormal cardiac muscle relaxation	J:76196
	abnormal heart ventricle morphology	J:76196
	abnormal myocardial fiber morphology	J:76196
	decreased heart left ventricle posterior wall thickness	J:76196
	decreased heart left ventricle septal wall thickness	J:76196
	decreased ventricle muscle contractility	J:76196
	dilated cardiomyopathy	J:76196
	increased susceptibility to induced morbidity/mortality	J:76196
Erbb2tm1Klee/Erbb2tm1Klee Tg(Ckmm-cre)1Lrsn/0 Not Specified	abnormal cardiac muscle relaxation	J:76196
	abnormal heart ventricle morphology	J:76196
	abnormal myocardial fiber morphology	J:76196
	decreased heart left ventricle posterior wall thickness	J:76196
	decreased heart left ventricle septal wall thickness	J:76196
	decreased ventricle muscle contractility	J:76196
	dilated cardiomyopathy	J:76196
Erbb2tm1Klee/Erbb2tm1Klee Tg(Mpz-cre)1Brn/0 involves: FVB/N	no abnormal phenotype detected	J:81239
Erbb2tm1Klee/Erbb2tm1Klee Tg(Nes-cre)1Atp/0 involves: C57BL/6 * FVB/N	abnormal colon morphology	J:81239
	abnormal enteric ganglia morphology	J:81239
	abnormal enteric neuron morphology	J:81239
	decreased body size	J:81239
	distended abdomen	J:81239
	postnatal growth retardation	J:81239
	premature death	J:81239
Erbb2tm1Mul/Erbb2tm1Mul involves: 129S1/Sv * 129X1/SvJ * BALB/c	abnormal blood circulation	J:74283
	abnormal paravertebral ganglion morphology	J:74283
	absent trabeculae carneae	J:74283
	embryonic lethality during organogenesis, complete penetrance	J:74283
	enlarged heart	J:74283
	irregular heartbeat	J:74283
Erbb2tm1Vrtn/Erbb2tm1Vrtn Not Specified	abnormal oligodendrocyte morphology	J:71775
	embryonic lethality during organogenesis, complete penetrance	J:71775
Erbb2tm2Mul/Erbb2tm2Mul involves: 129S1/Sv * 129X1/SvJ * BALB/c	abnormal paravertebral ganglion morphology	J:74283
	normal cardiovascular system phenotype	J:74283
Erbb2tm8(Erbb2)Mul/Erbb2+ Tg(MMTV-cre)7Mul/? involves: 129S1/Sv * 129X1/SvJ * FVB/N	abnormal mammary gland development	J:61202
	abnormal mammary gland lobule morphology	J:89255
	increased mammary gland tumor incidence	J:89255
Erbb2tm8(Erbb2)Mul/Erbb2tm8(Erbb2)Mul involves: 129S1/Sv * 129X1/SvJ * BALB/c	prenatal lethality	J:61202
Erbb2tm8.1(Erbb2)Mul/Erbb2+ involves: 129S1/Sv * 129X1/SvJ	normal nervous system phenotype	J:89255
	normal reproductive system phenotype	J:89255
Erbb2tm8.1(Erbb2)Mul/Erbb2tm8.1(Erbb2)Mul involves: 129S1/Sv * 129X1/SvJ	abnormal myocardial trabeculae morphology	J:89255
	abnormal paravertebral ganglion morphology	J:89255
	embryonic lethality during organogenesis, complete penetrance	J:89255
Tg(MMTV-Erbb2*,-cre)1Mul/0 involves: 129S1/Sv * 129X1/SvJ * FVB/N	increased mammary gland tumor incidence	J:133325
Tg(MMTV-Erbb2*,-cre)1Mul/0 involves: FVB	abnormal mammary gland morphology	J:198481
	decreased tumor latency	J:198481
	increased mammary gland tumor incidence	J:198481