64 phenotypes from 14 alleles in 15 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Aldh1a1tm1.1(cre/ERT2)Cai/Aldh1a1+ Slc6a3tm1c(KOMP)Wtsi/Slc6a3tm1c(KOMP)Wtsi involves: C57BL/6N * SJL	abnormal motor coordination/balance	J:280705
	normal behavior/neurological phenotype	J:280705
Slc6a3tm1(cre)Bkmn/Slc6a3tm1(cre)Bkmn involves: 129S1/Sv * 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:114466
Slc6a3tm1(cre)Xz/Slc6a3+ involves: 129S1/Sv	hyperactivity	J:174505
Slc6a3tm1(cre)Xz/Slc6a3+ involves: 129S1/Sv * C57BL/6 * SJL	no abnormal phenotype detected	J:115426
Slc6a3tm1.1(cre)Bkmn/Slc6a3tm1.1(cre)Bkmn involves: 129S1/Sv * 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:114466
Slc6a3tm1.1Asor/Slc6a3tm1.1Asor involves: 129X1/SvJ * C57BL/6J	no abnormal phenotype detected	J:183289
Slc6a3tm1.1Jaja/Slc6a3tm1.1Jaja B6.129-Slc6a3tm1.1Jaja	decreased dopamine level	J:180517
	decreased susceptibility to dopaminergic neuron neurotoxicity	J:180517
	normal mortality/aging	J:180517
	normal reproductive system phenotype	J:180517
Slc6a3tm1b(KOMP)Wtsi/Slc6a3+ C57BL/6N-Slc6a3tm1b(KOMP)Wtsi/J	hyperactivity	J:211773
	increased circulating sodium level	J:211773
	increased heart weight	J:211773
Slc6a3tm1b(KOMP)Wtsi/Slc6a3tm1b(KOMP)Wtsi C57BL/6N-Slc6a3tm1b(KOMP)Wtsi/J	abnormal tooth morphology	J:211773
	absent teeth	J:211773
Slc6a3tm1Hhg/Slc6a3tm1Hhg B6.129X1-Slc6a3tm1Hhg	abnormal CNS synaptic transmission	J:183177
	abnormal inhibitory postsynaptic currents	J:183177
	abnormal miniature inhibitory postsynaptic current frequency	J:183177
	increased locomotor activity	J:183177
Slc6a3tm1Hhg/Slc6a3tm1Hhg involves: 129X1/SvJ * C57BL/6J	abnormal dopaminergic neuron morphology	J:111041
	abnormal locomotor activation	J:111041
	abnormal neurotransmitter uptake	J:111041
	abnormal synaptic dopamine release	J:111041
	hyperactivity	J:111041
	impaired conditioned place preference behavior	J:111041
	increased dopamine level	J:111041
Slc6a3tm1Mca/Slc6a3tm1Mca B6.129P2-Slc6a3tm1Mca	enhanced long-term potentiation	J:89778
Slc6a3tm1Mca/Slc6a3tm1Mca involves: 129P2/OlaHsd	abnormal adenohypophysis morphology	J:41856
	abnormal maternal nurturing	J:31328
	abnormal pituitary gland physiology	J:41856
	abnormal pituitary secretion	J:41856
	abnormal spatial learning	J:79011
	adenohypophysis hypoplasia	J:41856
	decreased body size	J:109373
	decreased body weight	J:41856
	decreased dopamine level	J:31328, J:41856, J:59670, J:79010
	decreased dopaminergic neuron number	J:59670, J:109373
	decreased lactotroph cell number	J:41856
	decreased length of long bones	J:41856
	decreased somatotroph cell number	J:41856
	decreased vertical activity	J:109373
	disproportionate dwarf	J:41856
	hypopituitarism	J:41856
	impaired coordination	J:109373
	increased locomotor activity	J:31328, J:79011, J:109373
	increased thigmotaxis	J:109373
	lactation failure	J:41856
	pituitary intermediate lobe hypoplasia	J:41856
	postnatal growth retardation	J:31328, J:41856
	premature death	J:31328
	short stride length	J:109373
Slc6a3tm1Mca/Slc6a3tm1Mca involves: 129P2/OlaHsd * C57BL/6	abnormal response to novel odor	J:110704
	normal behavior/neurological phenotype	J:110704
	normal nervous system phenotype	J:110704
	normal taste/olfaction phenotype	J:110704
Slc6a3tm1Mca/Slc6a3tm1Mca involves: 129P2/OlaHsd * C57BL/6J	abnormal adenohypophysis morphology	J:93114
	increased exploration in new environment	J:93114
	postnatal growth retardation	J:93114
	small pituitary gland	J:93114
Slc6a3tm1Rbl/Slc6a3+ involves: 129S6/SvEvTac * C57BL/6J	decreased vertical activity	J:216661
Slc6a3tm1Rbl/Slc6a3tm1Rbl involves: 129S6/SvEvTac * C57BL/6J	abnormal behavior	J:216661, J:221936
	abnormal behavioral response to xenobiotic	J:216661
	abnormal inhibitory postsynaptic currents	J:216661
	abnormal neuron physiology	J:216661
	abnormal synaptic dopamine release	J:216661
	decreased physiological sensitivity to xenobiotic	J:216661
	decreased vertical activity	J:216661
	increased dopamine level	J:216661
	increased serotonin level	J:216661
	lethality, incomplete penetrance	J:221936
Slc6a3tm1Wzh/Slc6a3tm1Wzh involves: 129S1/Sv * C57BL/6	hyperactivity	J:168866
Slc6a3tm2(tTA)Xz/Slc6a3tm3(tetO)Xz involves: 129X1/SvJ * C57BL/6J	abnormal action potential	J:144671
	abnormal behavior	J:144671
	increased dopamine level	J:144671
Slc6a3tm2Mca/Slc6a3tm2Mca involves: 129S1/Sv * 129X1/SvJ	abnormal grooming behavior	J:176799
	abnormal physiological response to xenobiotic	J:67549
	abnormal response to novel object	J:67549
	decreased neurotransmitter release	J:67549
	normal growth/size/body region phenotype	J:67549
	increased dopamine level	J:67549
	increased exploration in new environment	J:67549
	increased locomotor activity	J:67549
	increased stereotypic behavior	J:176799
	increased vertical activity	J:67549
	normal nervous system phenotype	J:67549