Chm Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Chm
CHM Rab escort protein
MGI:892979

29 phenotypes from 5 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Chm^tm1.1Seab/Y involves: 129X1/SvJ	no abnormal phenotype detected	J:105458
Chm^tm1.1Seab/Chm^tm1.1Seab Tg(Six3-cre)69Frty/0 involves: 129X1/SvJ * C57BL/6 * DBA/2	abnormal retina morphology	J:105458
	abnormal rod electrophysiology	J:105458
	short photoreceptor outer segment	J:105458
	thin retina outer nuclear layer	J:105458
Chm^tm1.1Seab/Y Tg(Six3-cre)69Frty/0 involves: 129X1/SvJ * C57BL/6 * DBA/2	abnormal retina morphology	J:105458
	abnormal rod electrophysiology	J:105458
	short photoreceptor outer segment	J:105458
	thin retina outer nuclear layer	J:105458
Chm^tm1.2Seab/Chm⁺ involves: 129X1/SvJ	abnormal response/metabolism to endogenous compounds	J:105458
	abnormal retina morphology	J:105458
	abnormal retina pigmentation	J:105458
	abnormal rod electrophysiology	J:105458
	short photoreceptor outer segment	J:105458
Chm^tm1.3Seab/Chm⁺ involves: 129X1/SvJ	abnormal photoreceptor outer segment morphology	J:105458
	abnormal response/metabolism to endogenous compounds	J:105458
	abnormal retina morphology	J:105458
	abnormal retina pigment epithelium morphology	J:105458
	abnormal retina pigmentation	J:105458
	abnormal rod electrophysiology	J:105458
	retina photoreceptor degeneration	J:105458
	thin retina outer nuclear layer	J:105458
Chm^tm1Jvdh/Chm⁺ involves: 129P2/OlaHsd * C57BL/6	abnormal placenta labyrinth morphology	J:92328
	abnormal spongiotrophoblast layer morphology	J:92328
	abnormal trophoblast layer morphology	J:92328
	abnormal visceral yolk sac blood island morphology	J:92328
	abnormal visceral yolk sac morphology	J:92328
	abnormal vitelline vascular remodeling	J:92328
	decreased angiogenesis	J:92328
	decreased retina photoreceptor cell number	J:40673
	embryonic growth retardation	J:92328
	embryonic lethality during organogenesis, complete penetrance	J:92328
	failure of chorioallantoic fusion	J:92328
	prenatal lethality, complete penetrance	J:40673
	small ectoplacental cone	J:92328
	small placenta	J:92328
Chm^tm1Jvdh/Y involves: 129P2/OlaHsd * C57BL/6	abnormal placenta labyrinth morphology	J:92328
	abnormal spongiotrophoblast layer morphology	J:92328
	abnormal trophoblast layer morphology	J:92328
	abnormal visceral yolk sac blood island morphology	J:92328
	abnormal visceral yolk sac morphology	J:92328
	abnormal vitelline vascular remodeling	J:92328
	absent placental labyrinth	J:92328
	decreased angiogenesis	J:92328
	embryonic growth retardation	J:92328
	embryonic lethality during organogenesis, complete penetrance	J:92328
	failure of chorioallantoic fusion	J:92328
	prenatal lethality, complete penetrance	J:40673
	small ectoplacental cone	J:92328
	small placenta	J:92328
	thin placenta labyrinth	J:92328
Chm^tm1Jvdh/Chm⁺ involves: 129P2/OlaHsd * C57BL/6 * SMZ	prenatal lethality, incomplete penetrance	J:92328
Chm^tm1Jvdh/Chm⁺ involves: 129P2/OlaHsd * C57BL/6 * SMZ	normal vision/eye phenotype	J:92328
Chm^tm1Seab/Y involves: 129X1/SvJ	normal homeostasis/metabolism phenotype	J:105458

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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