Chm^tm1Ynshn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Chm^tm1Ynshn
• Name: CHM Rab escort protein; targeted mutation 1, Yin Shen
• MGI ID: MGI:8330142
• Synonyms: Chm^fl
• Gene: Chm Location: ChrX:111950290-112095214 bp, - strand Genetic Position: ChrX, 48.94 cM
• Alliance: Chm^tm1Ynshn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:377711
• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 4 was flanked by loxP sites. (J:377711)

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Chm Mutation: 16 strains or lines available

References

• Original: J:377711 Yan J, et al., Deficiency disrupts photoreceptor viability and synaptic integrity in a choroideremia mouse model. Cell Death Dis. 2025 Dec 22;16(1):914
• All: 1 reference(s)