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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Creb1
cAMP responsive element binding protein 1
MGI:88494
35 phenotypes from 7 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Creb1tm1.1Berd/Creb1tm1.1Berd
B6NHsd.129S4-Creb1tm1.1Berd
abnormal myotube morphology J:177923
enhanced skeletal muscle regeneration J:177923
increased myoblast proliferation J:177923
normal muscle phenotype J:177923
Creb1tm1.1Khk/Creb1tm1.1Khk
involves: C57BL/6J * FVB/N
normal homeostasis/metabolism phenotype J:210887
Creb1tm1Gsc/Creb1tm1Gsc
involves: 129S2/SvPas
abnormal behavioral response to addictive substance J:34605
abnormal CNS synaptic transmission J:20672
abnormal contextual conditioning behavior J:20672
abnormal cued conditioning behavior J:20672
abnormal spatial learning J:20672
abnormal stellate ganglion morphology J:121244
abnormal temporal memory J:20672
decreased behavioral withdrawal response J:34605
decreased survivor rate J:18749
decreased vertical activity J:34605
postnatal lethality J:18749
reduced long-term potentiation J:20672
small superior cervical ganglion J:121244
Creb1tm1Nes/Creb1tm1Nes
involves: C57BL/6J
abnormal single cell response J:164682
Creb1tm3.1Gsc/Creb1tm3.1Gsc
involves: 129P2/OlaHsd * C57BL/6
abnormal lung development J:171712
abnormal lung vasculature morphology J:171712
decreased fetal size J:171712
impaired lung alveolus development J:171712
lethality throughout fetal growth and development, incomplete penetrance J:171712
pale lung J:171712
small lung J:171712
Creb1tm3Gsc/Creb1tm3Gsc
Tg(Cyp17a1-icre)AJako/0
involves: 129P2/OlaHsd * C57BL/6 * SJL
decreased circulating testosterone level J:170888
decreased epididymis weight J:170888
decreased seminal vesicle weight J:170888
decreased testis weight J:170888
oligozoospermia J:170888
small testis J:170888
Creb1tm3Gsc/Creb1tm3Gsc
Tg(Dbh-icre)1Gsc/0
involves: 129P2/OlaHsd * C57BL/6
normal mortality/aging J:121244
normal nervous system phenotype J:121244
Creb1tm4Gsc/Creb1tm4Gsc
involves: 129P2/OlaHsd * C57BL/6
abnormal circadian behavior phase J:75993

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory