30 phenotypes from 11 alleles in 16 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cd4del/Cd4del C57BR/cdJ-Cd4del	abnormal immune system organ morphology	J:46692
	abnormal lymph node T cell domain morphology	J:46692
	abnormal spleen morphology	J:46692
	absent CD4-positive, alpha-beta T cells	J:46692
	decreased IgG level	J:46692
	decreased IgM level	J:46692
	decreased immunoglobulin level	J:46692
	increased CD8-positive, alpha-beta T cell number	J:46692
Cd4em1Litt/Cd4em1Litt involves: C57BL/6J	normal immune system phenotype	J:333574
Cd4m1Btlr/Cd4m1Btlr C57BL/6J-Cd4m1Btlr	absent CD4-positive, alpha-beta T cells	J:212900
	impaired humoral immune response	J:212900
Cd4maat/Cd4maat C57BL/6JAnu-Cd4maat/Apb	abnormal CD4-positive, alpha beta T cell morphology	J:104190
	abnormal double-positive T cell morphology	J:104190
	decreased CD4-positive, alpha-beta T cell number	J:104190
	increased CD8-positive, alpha-beta T cell number	J:104190
Cd4sesh/Cd4sesh C57BL/6JAnu-Cd4sesh/AnuApb	abnormal CD4-positive, alpha beta T cell morphology	J:104190
	abnormal double-positive T cell morphology	J:104190
	decreased T cell number	J:104190
Cd4thth/Cd4thth C57BL/6JSfdAnu-Cd4thth	absent CD4-positive, alpha-beta T cells	J:104190
Cd4tm1Jrp/Cd4tm1Jrp either: B6.129S2-Cd4tm1Jrp or B10.Cg-Cd4tm1Jrp	abnormal T cell differentiation	J:45168
	decreased CD4-positive, alpha-beta T cell number	J:45168
	decreased double-positive T cell number	J:45168
	increased CD8-positive, alpha-beta T cell number	J:45168
Cd4tm1Knw/Cd4tm1Knw B6.129S-Cd4tm1Knw/J	decreased CD4-positive, alpha-beta T cell number	J:87828
	increased CD8-positive, alpha-beta T cell number	J:87828
	increased susceptibility to parasitic infection	J:87828
Cd4tm1Knw/Cd4tm1Knw NOD.Cg-Cd4tm1Knw	decreased susceptibility to autoimmune diabetes	J:93553
Cd4tm1Litt/Cd4tm1Litt involves: 129S2/SvPas	abnormal CD4-positive, alpha-beta T cell physiology	J:50435
	absent CD4-positive, alpha-beta T cells	J:50435
	decreased CD4-positive, alpha-beta T cell number	J:158962
	decreased T cell proliferation	J:50435
	increased CD8-positive, alpha-beta T cell number	J:50435, J:158962
Cd4tm1Litt/Cd4tm1Nik Tg(Lck-cre)3778Nik/0 involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 * DBA/2	abnormal CD4-positive, alpha-beta T cell physiology	J:73479
	abnormal interleukin-4 secretion	J:73479
	abnormal T-helper 2 physiology	J:73479
	decreased T cell proliferation	J:73479
Cd4tm1Litt/Cd4tm1Nik Tg(Lck-cre)3785Nik/0 involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 * DBA/2	abnormal CD4-positive, alpha-beta T cell physiology	J:73479
	decreased CD4-positive, alpha-beta T cell number	J:73479
	increased CD8-positive, alpha-beta T cell number	J:73479
	increased T cell apoptosis	J:73479
	increased T cell proliferation	J:73479
Cd4tm1Litt/Cd4tm1Nik Tg(Lck-icre)3779Nik/0 involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 * DBA/2	abnormal CD4-positive, alpha-beta T cell physiology	J:73479
	decreased T cell proliferation	J:73479
Cd4tm1Mak/Cd4tm1Mak B6.129S2-Cd4tm1Mak/J	abnormal bile salt level	J:133047
	absent plasma cells	J:133047
	normal immune system phenotype	J:133047
Cd4tm1Mak/Cd4tm1Mak involves: 129S2/SvPas	normal immune system phenotype	J:110749
Cd4tm1Mak/Cd4tm1Mak involves: 129S2/SvPas * C57BL/6 * DBA/2	abnormal CD4-positive, alpha-beta T cell physiology	J:68957
	demyelination	J:92227
	increased CD8-positive, alpha-beta T cell number	J:68957
	increased susceptibility to Picornaviridae infection	J:92227
Cd4tm1Mak/Cd4tm1Mak PL.129S2(B6)-Cd4tm1Mak/Rdgz	brain inflammation	J:92227
	demyelination	J:92227
	increased susceptibility to Picornaviridae infection	J:92227
Cd4tm1Mak/Cd4tm1Mak SJL.129S2(B6)-Cd4tm1Mak/Rdgz	brain inflammation	J:92227
	demyelination	J:92227
	increased susceptibility to Picornaviridae infection	J:92227
Cd4tm1Nik/Cd4tm1Nik Tnfrsf4tm2(cre)Nik/Tnfrsf4+ involves: 129X1/SvJ	abnormal regulatory T cell physiology	J:152472