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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Apob
apolipoprotein B
MGI:88052
40 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Apobtm1Sgy/Apobtm1Sgy
Apoetm1Unc/Apoetm1Unc
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 		increased body weight J:41510
increased circulating cholesterol level J:41510
increased circulating triglyceride level J:41510
increased circulating VLDL cholesterol level J:41510
increased susceptibility to atherosclerosis J:41510
Apobtm2Sgy/Apobtm2Sgy
Apoetm1Unc/Apoetm1Unc
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 		abnormal cholesterol homeostasis J:41510
decreased body weight J:41510
decreased circulating cholesterol level J:41510
decreased susceptibility to atherosclerosis J:41510
increased circulating HDL cholesterol level J:41510
increased circulating triglyceride level J:41510
increased circulating VLDL cholesterol level J:41510
increased circulating VLDL triglyceride level J:41510
Apobtm2Sgy/Apobtm2Sgy
Apoetm1Unc/Apoetm1Unc
Lepob/Lepob
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 		abnormal circulating cholesterol level J:133453
atherosclerotic lesions J:133453
decreased circulating HDL cholesterol level J:133453
hyperglycemia J:133453
hypertension J:133453
impaired glucose tolerance J:133453
increased circulating cholesterol level J:133453
increased circulating free fatty acids level J:133453
increased circulating insulin level J:133453
increased circulating triglyceride level J:133453
increased circulating VLDL cholesterol level J:133453
obese J:133453
Apobtm2Sgy/Apobtm2Sgy
Ldlrtm1Her/Ldlrtm1Her
involves: 129S7/SvEvBrd * C57BL/6 		abnormal eye electrophysiology J:136142
abnormal retina pigment epithelium morphology J:136142
Apobtm2Sgy/Apobtm2Sgy
Ldlrtm1Her/Ldlrtm1Her
involves: 129S7/SvEvBrd * C57BL/6J 		abnormal aorta bulb morphology J:227165
abnormal heart ventricles weight J:227165
aortic valve stenosis J:227165
decreased cardiac muscle contractility J:227165
increased cardiac output J:227165
increased cardiac stroke volume J:227165
increased circulating cholesterol level J:227165
increased circulating insulin level J:227165
Apobtm2Sgy/Apobtm2Sgy
Ldlrtm1Her/Ldlrtm1Her
Lepob/Lepob
involves: 129S7/SvEvBrd * C57BL/6 		abnormal circulating cholesterol level J:133453
atherosclerotic lesions J:133453
decreased circulating HDL cholesterol level J:133453
hypertension J:133453
increased circulating cholesterol level J:133453
increased circulating free fatty acids level J:133453
increased circulating insulin level J:133453
increased circulating LDL cholesterol level J:133453
increased circulating triglyceride level J:133453
obese J:133453
Apobtm2Sgy/Apobtm2Sgy
Ldlrtm1Her/Ldlrtm1Her
Tg(Ins-Igf2)1Fbos/?
involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL 		abnormal aorta bulb morphology J:227165
abnormal aortic valve morphology J:227165
abnormal cardiovascular system physiology J:227165
abnormal fasting circulating glucose level J:227165
abnormal heart left ventricle morphology J:227165
abnormal heart ventricles weight J:227165
aortic valve stenosis J:227165
aortitis J:227165
calcified aortic valve J:227165
cardiac fibrosis J:227165
cardiac hypertrophy J:227165
decreased cardiac muscle contractility J:227165
heart left ventricle hypertrophy J:227165
increased cardiac output J:227165
increased cardiac stroke volume J:227165
increased circulating cholesterol level J:227165
increased circulating insulin level J:227165
small aortic valve J:227165
Apobtm2Sgy/Apobtm2Sgy
Ldlrtm1Her/Ldlrtm1Her
Tg(Ins-Igf2)1Fbos/?
involves: 129S7/SvEvBrd * C57BL/6 * SJL 		atherosclerotic lesions J:141333
impaired glucose tolerance J:141333
increased circulating glucose level J:141333
increased circulating insulin level J:141333
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory