73 phenotypes from 12 alleles in 11 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Agtr1aem1(IMPC)Rbrc/Agtr1aem1(IMPC)Rbrc C57BL/6NJcl-Agtr1aem1(IMPC)Rbrc/Rbrc	abnormal erythrocyte cell number	J:211773
	abnormal heart morphology	J:211773
	abnormal hematocrit	J:211773
	abnormal hemoglobin content	J:211773
	abnormal kidney morphology	J:211773
	abnormal mean corpuscular hemoglobin	J:211773
	abnormal platelet cell number	J:211773
	abnormal red blood cell distribution width	J:211773
	abnormal spleen morphology	J:211773
	enlarged heart	J:211773
	enlarged spleen	J:211773
	increased spleen weight	J:211773
	polycystic kidney	J:211773
Agtr1atm1.1Cof/Agtr1atm1.1Cof Hprt1tm1(Pck1-cre)Vhh/Hprt1+ involves: 129 * 129P2/OlaHsd	abnormal renal water reabsorption	J:172240
	decreased renal glomerular filtration rate	J:172240
	decreased systemic arterial systolic blood pressure	J:172240
Agtr1atm1.1Uky/Agtr1atm1.1Uky Tg(Fabp4-cre)1Rev/0 involves: C57BL/6 * C57BL/6N * SJL	abnormal adipose tissue development	J:192945
	normal adipose tissue phenotype	J:192945
	decreased white fat cell number	J:192945
	normal growth/size/body region phenotype	J:192945
	normal homeostasis/metabolism phenotype	J:192945
	increased white fat cell size	J:192945
Agtr1atm1Afu/Agtr1a+ involves: C57BL/6 * CBA * ICR	decreased systemic arterial systolic blood pressure	J:28041
	normal homeostasis/metabolism phenotype	J:28041
	hypotension	J:28041
Agtr1atm1Afu/Agtr1atm1Afu involves: C57BL/6 * CBA	abnormal kidney interstitium morphology	J:69294
	decreased susceptibility to injury	J:100334
	hypotension	J:91164
Agtr1atm1Afu/Agtr1atm1Afu involves: C57BL/6 * CBA * ICR	decreased systemic arterial systolic blood pressure	J:28041, J:107851
	hypotension	J:28041
	increased circulating renin level	J:28041
	increased fluid intake	J:107851
	increased renin activity	J:28041
Agtr1atm1Ecl/Agtr1atm1Ecl involves: 129S2/SvPas * C57BL/6	abnormal blood homeostasis	J:124206
	abnormal cardiovascular system physiology	J:124206
	abnormal heart left ventricle morphology	J:124206
	abnormal kidney physiology	J:124206
	abnormal kidney vasculature morphology	J:124206
	cardiac fibrosis	J:124206
	cardiac interstitial fibrosis	J:124206
	decreased body weight	J:124206
	decreased circulating angiotensin II level	J:124206
	decreased circulating renin level	J:124206
	decreased physiological sensitivity to xenobiotic	J:124206
	decreased urine creatinine level	J:124206
	decreased urine potassium level	J:124206
	high mean erythrocyte cell number	J:124206
	increased blood urea nitrogen level	J:124206
	increased heart weight	J:124206
	increased hemoglobin content	J:124206
	increased systemic arterial systolic blood pressure	J:124206
	increased urine osmolality	J:124206
	oliguria	J:124206
	renal fibrosis	J:124206
Agtr1atm1Tma/Agtr1atm1Tma involves: 129P2/OlaHsd * C57BL/6	abnormal juxtaglomerular apparatus morphology	J:36090
	abnormal kidney interlobular artery morphology	J:36090
	increased systemic arterial blood pressure	J:46007
	juxtaglomerular cell hyperplasia	J:36090
Agtr1atm1Uky/Agtr1atm1Uky Tg(Tagln-cre)1Her/0 involves: C57BL/6 * C57BL/6N * SJL	normal cardiovascular system phenotype	J:170230
Agtr1atm1Unc/Agtr1a+ involves: 129P2/OlaHsd * C57BL/6J	abnormal systemic arterial blood pressure	J:24354
	decreased systemic arterial blood pressure	J:24354
	decreased systemic arterial systolic blood pressure	J:24354
Agtr1atm1Unc/Agtr1atm1Unc involves: 129P2/OlaHsd	abnormal amygdala morphology	J:102774
	abnormal thalamus morphology	J:102774
Agtr1atm1Unc/Agtr1atm1Unc involves: 129P2/OlaHsd * C57BL/6	abnormal heart rate	J:137944
	abnormal physiological response to xenobiotic	J:137944
	abnormal response/metabolism to endogenous compounds	J:137944
	abnormal systemic arterial blood pressure	J:137944
	decreased heart rate	J:137944
	decreased heart weight	J:137944
	decreased mean systemic arterial blood pressure	J:137944
Agtr1atm1Unc/Agtr1atm1Unc involves: 129P2/OlaHsd * C57BL/6J	abnormal systemic arterial blood pressure	J:24354
	decreased systemic arterial blood pressure	J:24354
	decreased systemic arterial systolic blood pressure	J:24354
Agtr1atm2Tma/Agtr1atm2Tma involves: 129P2/OlaHsd * C57BL/6	abnormal juxtaglomerular apparatus morphology	J:36090
	abnormal kidney interlobular artery morphology	J:36090
	juxtaglomerular cell hyperplasia	J:36090
Agtr1atm3Tma/Agtr1atm3Tma Tg(Nphs1-cre)10Mska/0 involves: 129P2/OlaHsd * C57BL/6 * DBA/2	normal cardiovascular system phenotype	J:240316
	normal homeostasis/metabolism phenotype	J:240316
	normal renal/urinary system phenotype	J:240316
Hprt1tm1(Ggt1-Agtr1)Cof/Y involves: 129P2/OlaHsd	no abnormal phenotype detected	J:91837
Tg(Myh6-Agtr1a)4-7Vjd/0 FVB/N-Tg(Myh6-Agtr1a)4-7Vjd	abnormal impulse conducting system conduction	J:40974
	atrioventricular block	J:40974
	decreased heart rate	J:40974
	heart hyperplasia	J:40974
	increased heart atrium size	J:40974
	increased heart weight	J:40974
	perinatal lethality, incomplete penetrance	J:40974
	prolonged PR interval	J:40974
	prolonged QRS complex duration	J:40974