35 phenotypes from 10 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Chrna4tm1.1Stit/Chrna4tm1.1Stit B6.129X1-Chrna4tm1.1Stit	abnormal behavioral response to addictive substance	J:180872
	normal behavior/neurological phenotype	J:180872
	decreased body temperature	J:180872
	impaired conditioned place preference behavior	J:180872
Chrna4tm1.1Tmcg/Chrna4tm1.1Tmcg Slc6a3tm1(cre)Xz/Slc6a3+ involves: 129S/SvEv * 129S1/Sv * C57BL/6	abnormal synaptic dopamine release	J:174505
	enhanced behavioral response to nicotine	J:174505
	impaired behavioral response to nicotine	J:174505
	impaired conditioned place preference behavior	J:174505
Chrna4tm1.2Tmcg/Chrna4tm1.2Tmcg involves: 129S/SvEv * 129S1/Sv * C57BL/6	abnormal synaptic dopamine release	J:174505
	decreased neurotransmitter release	J:174505
	impaired behavioral response to nicotine	J:174505
	impaired conditioned place preference behavior	J:174505
Chrna4tm1Dra/Chrna4tm1Dra involves: 129S4/SvJae * C57BL/6	abnormal behavioral response to addictive substance	J:64208
	abnormal brain wave pattern	J:97020
	abnormal emotion/affect behavior	J:97020
	abnormal locomotor activation	J:64208
	abnormal response to new environment	J:64208
	normal behavior/neurological phenotype	J:125305
	decreased grooming behavior	J:64208
	increased anxiety-related response	J:64208
	increased susceptibility to pharmacologically induced seizures	J:97020
	increased vertical activity	J:64208
Chrna4tm1Jbou/Chrna4+ either: (involves: 129S4/SvJae * 129X1/SvJ * C57BL/6J) or (involves: 129X1/SvJ * C57BL/6J)	abnormal brain wave pattern	J:118273
	abnormal inhibitory postsynaptic currents	J:118273
	abnormal nervous system physiology	J:118273
	behavioral arrest	J:118273
	clonic seizures	J:118273
	seizures	J:118273
Chrna4tm1Jbou/Chrna4tm1Jbou either: (involves: 129S4/SvJae * 129X1/SvJ * C57BL/6J) or (involves: 129X1/SvJ * C57BL/6J)	abnormal brain wave pattern	J:118273
	abnormal nervous system physiology	J:118273
	behavioral arrest	J:118273
	clonic seizures	J:118273
	seizures	J:118273
Chrna4tm1Jpc/Chrna4tm1Jpc B6.Cg-Chrna4tm1Jpc	normal nervous system phenotype	J:77377
Chrna4tm1Jpc/Chrna4tm1Jpc involves: C57BL/6	abnormal brain morphology	J:54505
	abnormal nicotine-mediated receptor currents	J:54505
	decreased chemically-elicited antinociception	J:54505
	decreased IgG level	J:103908
	decreased immunoglobulin level	J:103908
	normal immune system phenotype	J:103908
	increased IgG level	J:103908
Chrna4tm1Lst/Chrna4+ involves: C57BL/6	abnormal motor learning	J:67863
	normal behavior/neurological phenotype	J:67863
	enhanced behavioral response to nicotine	J:67863
	impaired behavioral response to addictive substance	J:67863
	increased anxiety-related response	J:67863
	increased exploration in new environment	J:67863
Chrna4tm1Lst/Chrna4tm1Lst involves: C57BL/6	decreased dopaminergic neuron number	J:67863
	neonatal lethality, complete penetrance	J:67863
Chrna4tm2.1Dra/Chrna4+ B6.129S1-Chrna4tm2.1Dra	abnormal behavioral response to addictive substance	J:125305
	normal behavior/neurological phenotype	J:125305
	impaired behavioral response to nicotine	J:125305
Chrna4tm2.1Dra/Chrna4+ involves: 129S1/Sv * C57BL/6 * CD-1	abnormal behavioral response to addictive substance	J:125305
	normal behavior/neurological phenotype	J:125305
	impaired behavioral response to nicotine	J:125305
Chrna4tm2.1Dra/Chrna4+ involves: 129S1/Sv * CD-1	abnormal behavioral response to addictive substance	J:125305
	normal behavior/neurological phenotype	J:125305
	impaired behavioral response to nicotine	J:125305
Chrna4tm2Jbou/Chrna4+ either: (involves: 129S4/SvJae * 129X1/SvJ * C57BL/6J) or (involves: 129X1/SvJ * C57BL/6J)	abnormal brain wave pattern	J:118273
	abnormal nervous system physiology	J:118273
	behavioral arrest	J:118273
	clonic seizures	J:118273
	seizures	J:118273
Chrna4tm2Jbou/Chrna4tm2Jbou either: (involves: 129S4/SvJae * 129X1/SvJ * C57BL/6J) or (involves: 129X1/SvJ * C57BL/6J)	abnormal brain wave pattern	J:118273
	abnormal nervous system physiology	J:118273
	behavioral arrest	J:118273
	clonic seizures	J:118273
	seizures	J:118273
Chrna4tm2Lst/Chrna4tm2Lst involves: 129S1/Sv * C57BL/6	enhanced behavioral response to nicotine	J:93873
	enhanced conditioned place preference behavior	J:93873