Zmiz1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Zmiz1
zinc finger, MIZ-type containing 1
MGI:3040693

25 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tg(Mx1-cre)1Cgn/0 Zmiz1^{tm1c(EUCOMM)Hmgu}/Zmiz1^{tm1c(EUCOMM)Hmgu} involves: C57BL/6 * C57BL/6J * C57BL/6N * CBA/J	decreased B cell number	J:234445
	decreased incidence of induced tumors	J:234445
	decreased NK cell number	J:234445
	decreased T cell number	J:234445
	increased ileal goblet cell number	J:234445
	thymus hypoplasia	J:234445
Tg(Vil1-cre/ERT2)23Syr/0 Zmiz1^{tm1c(EUCOMM)Hmgu}/Zmiz1^{tm1c(EUCOMM)Hmgu} involves: C57BL/6 * C57BL/6N * DBA/2	normal digestive/alimentary phenotype	J:234445
Zmiz1^tm1Zsu/Zmiz1⁺ involves: 129S6/SvEvTac * C57BL/6J	preweaning lethality, incomplete penetrance	J:128915
Zmiz1^tm1Zsu/Zmiz1^tm1Zsu involves: 129S6/SvEvTac * C57BL/6J	abnormal capillary morphology	J:128915
	abnormal dorsal aorta morphology	J:128915
	abnormal heart atrium morphology	J:128915
	abnormal heart valve morphology	J:128915
	abnormal perineural vascular plexus morphology	J:128915
	abnormal pharyngeal arch artery morphology	J:128915
	abnormal vascular branching morphogenesis	J:128915
	abnormal vascular development	J:128915
	abnormal vitelline vascular remodeling	J:128915
	abnormal vitelline vasculature morphology	J:128915
	decreased cell proliferation	J:128915
	decreased embryo size	J:128915
	dilated dorsal aorta	J:128915
	embryonic lethality during organogenesis, complete penetrance	J:128915
	normal hematopoietic system phenotype	J:128915
	pale yolk sac	J:128915
	pallor	J:128915

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23