Ccn6 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ccn6
cellular communication network factor 6
MGI:2685581

16 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Aurka^tm1.1Tvd/Aurka^tm1.1Tvd Ccn6^tm1(cre)Mawa/Ccn6⁺ involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J	abnormal sperm head morphology	J:321647
	abnormal sperm midpiece morphology	J:321647
	abnormal sperm motility	J:321647
	abnormal sperm physiology	J:321647
	decreased litter size	J:321647
	decreased testis weight	J:321647
	increased male germ cell apoptosis	J:321647
	increased sperm progressive motility	J:321647
	kinked sperm flagellum	J:321647
	multiflagellated sperm	J:321647
	oligozoospermia	J:321647
	reduced male fertility	J:321647
	small testis	J:321647
	teratozoospermia	J:321647
Ccn6^tm1.1Cgkl/Ccn6^tm1.1Cgkl Tg(MMTV-cre)1Mam/0 Tg(MMTV-PyVT)634Mul/0 FVB/N-Ccn6^tm1.1Cgkl Tg(MMTV-cre)1Mam Tg(MMTV-PyVT)634Mul	increased mammary adenocarcinoma incidence	J:241259
	increased metastatic potential	J:241259

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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