91 phenotypes from 5 alleles in 12 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
H2az2Tg(Wnt1-cre)11Rth/H2az2+ Kmt2dtm2.1Kaig/Kmt2d+ involves: C57BL/6J * CBA/J	abnormal ear shape	J:294895
	abnormal presphenoid bone morphology	J:294895
	abnormal snout morphology	J:294895
	broad face	J:294895
	domed cranium	J:294895
	postnatal growth retardation	J:294895
	short nasal bone	J:294895
	small basisphenoid bone	J:294895
	small presphenoid bone	J:294895
H2az2Tg(Wnt1-cre)11Rth/H2az2+ Kmt2dtm2.1Kaig/Kmt2dtm2.1Kaig involves: C57BL/6J * CBA/J	abnormal basisphenoid bone morphology	J:294895
	abnormal chondrocyte morphology	J:294895
	abnormal cranial neural crest cell morphology	J:294895
	abnormal endochondral bone ossification	J:294895
	abnormal hyoid bone morphology	J:294895
	abnormal neurocranium morphology	J:294895
	abnormal osteoblast morphology	J:294895
	abnormal palatal shelf morphology	J:294895
	abnormal palatine bone morphology	J:294895
	abnormal presphenoid bone morphology	J:294895
	abnormal pterygoid process morphology	J:294895
	abnormal temporal bone tympanic part morphology	J:294895
	abnormal viscerocranium morphology	J:294895
	cleft palate	J:294895
	face hypoplasia	J:294895
	glossoptosis	J:294895
	mandible hypoplasia	J:294895
	mandibular condyloid process hypoplasia	J:294895
	neonatal lethality, complete penetrance	J:294895
	short frontal bone	J:294895
	short nasal bone	J:294895
	small basisphenoid bone	J:294895
	small presphenoid bone	J:294895
Kmt2dbapa/Kmt2dbapa BALB/cJ-Kmt2dbapa	abnormal gait	J:290290
	abnormal motor capabilities/coordination/movement	J:290290
	abnormal pinna reflex	J:290290
	decreased coping response	J:290290
	hyporesponsive to tactile stimuli	J:290290
	impaired coordination	J:290290
	impaired righting response	J:290290
	increased grooming behavior	J:290290
	increased locomotor activity	J:290290
	increased vertical activity	J:290290
	limb grasping	J:227974
	short stride length	J:290290
Kmt2dGt(RRT024)Byg/Kmt2d+ involves: 129P2/OlaHsd	decreased body fat mass	J:301497
	decreased body length	J:301083
	decreased body size	J:301083
	decreased body weight	J:301083, J:301497
	decreased neuron number	J:301083
	decreased susceptibility to diet-induced obesity	J:301497
	improved glucose tolerance	J:301497
	increased bile salt level	J:301497
	increased insulin sensitivity	J:301497
Kmt2dGt(RRT024)Byg/Kmt2d+ involves: 129P2/OlaHsd * C57BL/6J	abnormal dentate gyrus morphology	J:225779
	abnormal hippocampus granule cell layer	J:225779
	abnormal inner ear canal morphology	J:225779
	abnormal object recognition memory	J:225779
	decreased body weight	J:225779
	flattened snout	J:225779
	impaired contextual conditioning behavior	J:225779
	impaired spatial learning	J:225779
	short maxilla	J:225779
Kmt2dGt(RRT024)Byg/Kmt2dGt(RRT024)Byg involves: 129P2/OlaHsd	embryonic lethality prior to organogenesis	J:301497
Kmt2dGt(RRT024)Byg/Kmt2dGt(RRT024)Byg involves: 129P2/OlaHsd * C57BL/6J	embryonic lethality during organogenesis, complete penetrance	J:225779
Kmt2dGt(XT0709)Wtsi/Kmt2dGt(XT0709)Wtsi involves: 129P2/OlaHsd	embryonic lethality during organogenesis, complete penetrance	J:207891
Kmt2dtm1.1Kaig/Kmt2d+ Cd19tm1(cre)Cgn/Cd19+ involves: 129P2/OlaHsd * C57BL/6	increased germinal center B cell number	J:228913
	increased spleen germinal center size	J:228913
Kmt2dtm1.1Kaig/Kmt2d+ Tmem163Tg(ACTB-cre)2Mrt/0 B6.Cg-Kmt2dtm1.1Kaig Tg(ACTB-cre)2Mrt	abnormal heart echocardiography feature	J:229890
	normal cardiovascular system phenotype	J:229890
Kmt2dtm1.1Kaig/Kmt2dtm1.1Kaig Cd19tm1(cre)Cgn/Cd19+ involves: 129P2/OlaHsd * C57BL/6	abnormal B cell differentiation	J:228913
	decreased B cell number	J:228913
	decreased follicular B cell number	J:228913
	decreased IgG1 level	J:228913
	decreased IgM level	J:228913
	decreased mature B cell number	J:228913
	normal immune system phenotype	J:228913
	increased B cell proliferation	J:228913
	increased germinal center B cell number	J:228913
	increased spleen germinal center number	J:228913
	increased spleen germinal center size	J:228913
Kmt2dtm1.1Kaig/Kmt2dtm1.1Kaig Ighg1tm1(cre)Cgn/Ighg1+ involves: 129P2/OlaHsd * C57BL/6	normal immune system phenotype	J:228913
Kmt2dtm1.1Kaig/Kmt2dtm1.1Kaig Mesp1tm2(cre)Ysa/Mesp1+ B6.Cg-Mesp1tm2(cre)Ysa Kmt2dtm1.1Kaig	abnormal heart tube morphology	J:229890
	embryonic growth retardation	J:229890
	embryonic lethality during organogenesis, complete penetrance	J:229890
	pericardial edema	J:229890
Kmt2dtm1.1Kaig/Kmt2dtm1.1Kaig Myf5tm3(cre)Sor/Myf5+ involves: 129S4/SvJaeSor * C57BL/6J	abnormal brown fat cell differentiation	J:207891
	abnormal muscle morphology	J:207891
	decreased brown adipose tissue amount	J:207891
	decreased muscle weight	J:207891
	neonatal lethality, complete penetrance	J:207891
	respiratory failure	J:207891
Kmt2dtm1.1Kaig/Kmt2dtm1.1Kaig Tg(Mef2c-cre)2Blk/0 B6.Cg-Kmt2dtm1.1Kaig Tg(Mef2c-cre)2Blk	abnormal interventricular septum morphology	J:229890
	embryonic lethality during organogenesis, complete penetrance	J:229890
	persistent truncus arteriosus	J:229890
Kmt2dtm1.1Kaig/Kmt2dtm1.1Kaig Tg(Nkx2-1-cre)2Sand/0 involves: C57BL/6	decreased circulating glucose level	J:301083
	decreased neuron number	J:301083
	impaired neuron differentiation	J:301083
Kmt2dtm1.1Kaig/Kmt2dtm1.1Kaig Tg(Tnnt2-cre)5Blh/0 B6.Cg-Kmt2dtm1.1Kaig Tg(Tnnt2-cre)5Blh	abnormal fetal cardiomyocyte physiology	J:229890
	abnormal interventricular septum morphology	J:229890
	normal cardiovascular system phenotype	J:229890
	decreased fetal cardiomyocyte proliferation	J:229890
	embryonic lethality during organogenesis, complete penetrance	J:229890
	thin myocardium compact layer	J:229890
Kmt2dtm1.1Kaig/Kmt2dtm1.1Kaig Tmem163Tg(ACTB-cre)2Mrt/0 B6.Cg-Kmt2dtm1.1Kaig Tg(ACTB-cre)2Mrt	absent head fold	J:229890
	absent somites	J:229890
	embryonic lethality between somite formation and embryo turning, complete penetrance	J:229890
Kmt2dtm2.1Kaig/Kmt2dtm2.1Kaig Tg(Sox10-cre)1Wdr/0 involves: C57BL/6 * C57BL/6J * CBA	abnormal basicranium morphology	J:294895
	face hypoplasia	J:294895
	mandible hypoplasia	J:294895
	short frontal bone	J:294895
	short nasal bone	J:294895