39 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Shank2em2(IMPC)Rbrc/Shank2em2(IMPC)Rbrc C57BL/6NJcl-Shank2em2(IMPC)Rbrc/Rbrc	abnormal behavior	J:211773
	abnormal locomotor behavior	J:211773
	abnormal neutrophil cell number	J:211773
	decreased erythrocyte cell number	J:211773
	hyperactivity	J:211773
	increased bone mineral content	J:211773
	increased thigmotaxis	J:211773
	limb grasping	J:211773
Shank2tm1.1Bcgen/Shank2tm1.1Bcgen Tg(Pcp2-cre)2Mpin/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal excitatory synapse morphology	J:237188
	abnormal miniature excitatory postsynaptic currents	J:237188
	impaired coordination	J:237188
	increased anxiety-related response	J:237188
	increased stereotypic behavior	J:237188
Shank2tm1.1Tmb/Shank2+ B6.129-Shank2tm1.1Tmb	abnormal excitatory postsynaptic potential	J:186719
	increased anxiety-related response	J:186719
	increased locomotor activity	J:186719
	postnatal lethality, incomplete penetrance	J:186719
Shank2tm1.1Tmb/Shank2tm1.1Tmb B6.129-Shank2tm1.1Tmb	abnormal dendritic spine morphology	J:186719
	abnormal excitatory postsynaptic potential	J:186719
	abnormal miniature excitatory postsynaptic currents	J:186719
	abnormal motor capabilities/coordination/movement	J:186719
	abnormal response to novelty	J:186719
	abnormal sexual interaction	J:186719
	abnormal social investigation	J:186719
	abnormal vocalization	J:186719
	decreased body weight	J:186719
	enhanced long-term potentiation	J:186719
	impaired righting response	J:186719
	improved righting response	J:186719
	increased anxiety-related response	J:186719
	increased grooming behavior	J:186719
	increased locomotor activity	J:186719
	increased stereotypic behavior	J:186719
	limb grasping	J:186719
	postnatal lethality, incomplete penetrance	J:186719
Shank2tm1Mgle/Shank2+ B6.129S4-Shank2tm1Mgle	normal behavior/neurological phenotype	J:186718
	hyperactivity	J:186718
Shank2tm1Mgle/Shank2tm1Mgle B6.129S4-Shank2tm1Mgle	abnormal cerebellar molecular layer	J:237188
	abnormal excitatory synapse morphology	J:237188
	abnormal learning/memory/conditioning	J:186718
	abnormal miniature excitatory postsynaptic currents	J:237188
	abnormal nervous system physiology	J:186718
	abnormal nest building behavior	J:186718
	abnormal pup retrieval	J:186718
	abnormal social investigation	J:186718
	abnormal spatial learning	J:186718
	abnormal voluntary movement	J:186718
	decreased vocalization	J:186718
	impaired coordination	J:237188
	increased anxiety-related response	J:186718, J:237188
	increased grooming behavior	J:186718
	increased locomotor activity	J:186718
	normal nervous system phenotype	J:186718
	reduced long-term depression	J:186718
	reduced long-term potentiation	J:186718