42 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Aldh1a3tm1Gdu/Aldh1a3+ Chd7Gt(S20-7E1)Sor/Chd7+ involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6J	abnormal semicircular canal morphology	J:314662
Aldh1a3tm1Gdu/Aldh1a3tm1Gdu Chd7Gt(S20-7E1)Sor/Chd7+ involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6J	abnormal semicircular canal morphology	J:314662
Chd7Gt(S20-7E1)Sor/Chd7+ Arb2aTg(Tyr)TpNpin/Arb2a+ involves: 129S4/SvJaeSor * C57BL/6 * FVB/N	abnormal optic fissure closure	J:260599
	circling	J:260599
	decreased body size	J:260599
	postnatal lethality, incomplete penetrance	J:260599
	prenatal lethality, incomplete penetrance	J:260599
	retina coloboma	J:260599
	sex reversal	J:260599
Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze/Gt(ROSA)26Sor+ Tg(Neurog1-cre)1Jejo/0 involves: 129S * C57BL/6 * SJL/J	abnormal vestibulocochlear ganglion morphology	J:310063
Chd7Gt(XK403)Byg/Chd7+ Fgf8tm1.2Mrt/Fgf8+ either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * CD-1)	abnormal fourth pharyngeal arch artery morphology	J:154590
Chd7Gt(XK403)Byg/Chd7+ Tbx1tm1Bld/Tbx1+ either: (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6) or (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CD-1)	abnormal ear development	J:154590
	abnormal subclavian artery morphology	J:154590
	absent fourth pharyngeal arch artery	J:154590
	ectopic thymus	J:154590
	interrupted aortic arch	J:154590
Chd7Gt(XK403)Byg/Chd7+ Fgf8tm2Mrt/Fgf8+ involves: 129 * 129P2/OlaHsd * C57BL/6J * DBA/2J	abnormal inferior colliculus morphology	J:207892
	absent cerebellum vermis	J:207892
	small cerebellum	J:207892
Chd7tm1.1Dmm/Chd7tm1.1Dmm Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze/Gt(ROSA)26Sor+ Shhtm1(EGFP/cre)Cjt/Shh+ involves: 129S1/SvlmJ * 129S6/SvEvTac * C57BL/6J * SJL/J	normal hearing/vestibular/ear phenotype	J:310063
Chd7tm1.1Dmm/Chd7tm1.1Dmm Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze/Gt(ROSA)26Sor+ Tg(Atoh1-cre)1Bfri/0 involves: 129 * C57BL/6 * C57BL/6NCrl * CBA	normal hearing/vestibular/ear phenotype	J:310063
Chd7tm2a(EUCOMM)Wtsi/Chd7tm2a(EUCOMM)Wtsi E2f1Tg(Wnt1-cre)2Sor/E2f1+ Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ involves: 129 * C3H * C57BL/6 * C57BL/6N	abnormal conotruncal ridge morphology	J:298597
	abnormal cranial neural crest cell migration	J:298597
	abnormal embryonic tissue physiology	J:298597
	abnormal pharyngeal arch morphology	J:298597
	double outlet right ventricle	J:298597
	impaired cranial neural crest cell differentiation	J:298597
	interrupted aortic arch, type b	J:298597
	perinatal lethality, complete penetrance	J:298597
	pulmonary trunk hypoplasia	J:298597
	small frontal bone	J:298597
	small mandible	J:298597
	small maxilla	J:298597
	ventricular septal defect	J:298597
Chd7tm2c(EUCOMM)Wtsi/Chd7tm2c(EUCOMM)Wtsi Tg(Atoh1-cre)1Bfri/0 Tg(Nes-Reln)#Cur/0 involves: C57BL/6 * C57BL/6J * C57BL/6N * CBA * FVB	abnormal cerebellar lobule formation	J:242933
	normal nervous system phenotype	J:242933
Chd7Whi/Chd7+ Tbx1tm1Bld/Tbx1+ B6.Cg-Chd7Whi Tbx1tm1Bld	abnormal lateral semicircular canal morphology	J:154590
	abnormal posterior semicircular canal morphology	J:154590
	absent lateral semicircular canal	J:154590
Chd7Whi/Chd7+ Fgfr1Hspy/Fgfr1+ C3HeB/FeJ-Chd7Whi Fgfr1Hspy	abnormal heart morphology	J:161880
	choanal atresia	J:161880
	cleft palate	J:161880
	normal nervous system phenotype	J:161880
	perinatal lethality, complete penetrance	J:161880
	preweaning lethality, complete penetrance	J:161880
	normal reproductive system phenotype	J:161880