Aldh1a3^tm1Gdu
Targeted Allele Detail

Summary

• Symbol: Aldh1a3^tm1Gdu
• Name: aldehyde dehydrogenase family 1, subfamily A3; targeted mutation 1, Gregg Duester
• MGI ID: MGI:3512079
• Synonyms: Raldh3^-
• Gene: Aldh1a3 Location: Chr7:66040640-66077225 bp, - strand Genetic Position: Chr7, 35.73 cM, cytoband C
• Alliance: Aldh1a3^tm1Gdu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:108515
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 11 was removed via cre mediated recombination. Retinoic acid activity was absent from the ventral retina and olfactory pit at E10.5. (J:108515)

Expression

In Mice Carrying this Mutation:

29 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Aldh1a3 Mutation: 25 strains or lines available

References

• Original: J:108515 Molotkov A, et al., Retinoic acid guides eye morphogenetic movements via paracrine signaling but is unnecessary for retinal dorsoventral patterning. Development. 2006 May;133(10):1901-10
• All: 13 reference(s)