Cpeb2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cpeb2
cytoplasmic polyadenylation element binding protein 2
MGI:2442640

15 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Chat^tm2(cre)Lowl/Chat⁺ Cpeb2^tm1.1Yshu/Cpeb2^tm1.1Yshu involves: C57BL/6 * C57BL/6J * C57BL/6NJ * SJL/J	abnormal breathing pattern	J:237513
	abnormal whole-body plethysmography	J:237513
	apnea	J:237513
	decreased pulmonary respiratory rate	J:237513
	increased acetylcholine level	J:237513
	increased airway responsiveness	J:237513
	increased brain choline acetyltransferase activity	J:237513
Cpeb2^tm1.1Yshu/Cpeb2^tm1.1Yshu Tg(Nes-cre)1Kln/0 involves: C57BL/6 * C57BL/6J * SJL/J	abnormal breathing pattern	J:237513
	abnormal whole-body plethysmography	J:237513
	apnea	J:237513
	decreased pulmonary respiratory rate	J:237513
	increased acetylcholine level	J:237513
	increased brain choline acetyltransferase activity	J:237513
	respiratory failure	J:237513
Cpeb2^tm1.2Yshu/Cpeb2^tm1.2Yshu involves: 129S/Sv * C57BL/6 * C57BL/6J * SJL/J	abnormal breathing pattern	J:237513
	abnormal parasympathetic nervous system physiology	J:237513
	abnormal parasympathetic neuron morphology	J:237513
	abnormal whole-body plethysmography	J:237513
	apnea	J:237513
	bronchoconstriction	J:237513
	decreased heart rate	J:237513
	decreased pulmonary respiratory rate	J:237513
	normal growth/size/body region phenotype	J:237513
	increased acetylcholine level	J:237513
	increased brain choline acetyltransferase activity	J:237513
	normal nervous system phenotype	J:237513
	postnatal lethality, incomplete penetrance	J:237513
	respiratory failure	J:237513

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23