Zfp750 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Zfp750
zinc finger protein 750
MGI:2442210

29 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Zfp750^em1(IMPC)J/Zfp750^em1(IMPC)J C57BL/6NJ-Zfp750^em1(IMPC)J/J	preweaning lethality, complete penetrance	J:211773
Zfp750^{tm1b(EUCOMM)Wtsi}/Zfp750^{tm1b(EUCOMM)Wtsi} B6(Cg)-Zfp750^{tm1b(EUCOMM)Wtsi}	abnormal ceramide level	J:335426
	abnormal cholesterol homeostasis	J:335426
	abnormal corneocyte envelope morphology	J:335426
	abnormal enzyme/coenzyme level	J:335426
	abnormal epidermal lamellar body morphology	J:335426
	abnormal epidermal stem cell proliferation	J:335426
	abnormal epidermis stratum corneum morphology	J:335426
	abnormal epidermis stratum granulosum morphology	J:335426
	abnormal keratinocyte differentiation	J:335426
	abnormal lipid metabolism	J:335426
	abnormal phospholipid level	J:335426
	abnormal skin appearance	J:335426
	abnormal skin development	J:335426
	abnormal sphingomyelin level	J:335426
	abnormal stratum corneum lipid matrix formation	J:335426
	absent eyelids	J:335426
	absent gastric milk in neonates	J:335426
	decreased birth weight	J:335426
	decreased keratohyalin granule size	J:335426
	decreased triglyceride level	J:335426
	dehydration	J:335426
	eyelids open at birth	J:335426
	impaired skin barrier function	J:335426
	neonatal lethality, complete penetrance	J:335426
	shiny skin	J:335426
	thin epidermis	J:335426
	weight loss	J:335426
	wrinkled skin	J:335426

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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