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Zfp750 Gene Detail
Summary
  • Symbol
    Zfp750
  • Name
    zinc finger protein 750
  • Synonyms
    A030007D23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442210
    NCBI Gene: 319530
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:121401804-121410159 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 85.49 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    148 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442210
 protein coding gene Chr11:121401802-121410168 (-)
129S1/SvImJ ENSMUSG00200050980
 protein coding gene Chr11:118765681-118774037 (-)
A/J ENSMUSG00195028288
 protein coding gene Chr11:118441749-118450104 (-)
AKR/J ENSMUSG00220023429
 protein coding gene Chr11:118592097-118600454 (-)
BALB/cJ ENSMUSG00180045961
 protein coding gene Chr11:118738298-118746650 (-)
C3H/HeJ ENSMUSG00175045036
 protein coding gene Chr11:118692143-118700498 (-)
C57BL/6NJ ENSMUSG00215045750
 protein coding gene Chr11:118262225-118270580 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017567
 protein coding gene Chr11:117408494-117416812 (-)
CAST/EiJ ENSTCUG00005032022
 protein coding gene Chr11:118100414-118108803 (-)
CBA/J ENSMUSG00210048202
 protein coding gene Chr11:118406182-118414537 (-)
DBA/2J ENSMUSG00185022861
 protein coding gene Chr11:118719331-118727686 (-)
FVB/NJ ENSMUSG00205027897
 protein coding gene Chr11:118564965-118573325 (-)
JF1/MsJ ENSUMUG00000044603
 protein coding gene Chr11:119003283-119011665 (-)
LP/J ENSMUSG00230049879
 protein coding gene Chr11:119780494-119788844 (-)
NOD/ShiLtJ ENSMUSG00190044772
 protein coding gene Chr11:118790559-118798916 (-)
NZO/HlLtJ ENSMUSG00225026721
 protein coding gene Chr11:121950541-121958893 (-)
PWK/PhJ ENSLUMG00010019121
 protein coding gene Chr11:118504452-118512826 (-)
SPRET/EiJ ENSMSPG00010033577
 protein coding gene Chr11:119145178-119148429 (-)
WSB/EiJ ENSIUOG00005037737
 protein coding gene Chr11:118529402-118537796 (-)



Homology
more
  • Human Ortholog
    ZNF750, zinc finger protein 750
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF750, zinc finger protein 750
  • Synonyms
    SLDPE, ZFP750
  • Links
    NCBI Gene ID: 79755
    UniProt: Q32MQ0

  • Chr Location
    17q25.3; chr17:82829434-82840022 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    29 phenotypes from 2 alleles in 2 genetic backgrounds
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele die shortly after birth with absent eyelids and exhibit shiny, wrinkled skin, dehydration, weight loss, thin epidermis, impaired skin barrier function, and alterations in epidermal terminal differentiation and lipid composition.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    37
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    827
  • Tissues
    47
  • cDNA Data
    28
  • Literature Summary
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000039238 Ensembl Gene Model | MGI Sequence Detail 8356 C57BL/6J ±  kb
    transcript ENSMUST00000092298 Ensembl | MGI Sequence Detail 3232 Not Applicable  
    polypeptide ENSMUSP00000089951 Ensembl | MGI Sequence Detail 703 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 30
      cDNA 28
      Primer pair 1
      Other 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 43
      Developmental Gene Expression 8
      Gene Ontology 6
      Phenotypes 11
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:390780 Qasrawi F, et al., DeltaNP63 regulates epithelial stratification and differentiation in the murine ureter. Am J Physiol Renal Physiol. 2026 Aug 1;331(2):F286-F303
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory