Cmtr2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cmtr2
cap methyltransferase 2
MGI:2384580

21 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cmtr2^em2Cya/Cmtr2^em2Cya Plekha5^{Tg(AMH-cre)1Flor}/Plekha5⁺ involves: C57BL/6 * C57BL/6J * SJL	normal reproductive system phenotype	J:389086
Cmtr2^em2Cya/Cmtr2^em2Cya Tg(Ddx4-cre)1Dcas/0 involves: C57BL/6J * FVB	abnormal male meiosis	J:389086
	abnormal seminiferous tubule morphology	J:389086
	abnormal spermatocyte morphology	J:389086
	arrest of male meiosis	J:389086
	arrest of spermatogenesis	J:389086
	azoospermia	J:389086
	decreased male germ cell number	J:389086
	decreased spermatid number	J:389086
	impaired DNA repair	J:389086
	increased testis apoptosis	J:389086
	male infertility	J:389086
	small testis	J:389086
	testicular atrophy	J:389086
Cmtr2^em2Cya/Cmtr2^em2Cya Tg(Stra8-icre)1Reb/0 Not Specified	abnormal seminiferous tubule morphology	J:389086
	abnormal spermatocyte morphology	J:389086
	arrest of male meiosis	J:389086
	decreased male germ cell number	J:389086
	decreased spermatid number	J:389086
Cmtr2^{tm1.1(KOMP)Vlcg}/Cmtr2⁺ B6N(Cg)-Cmtr2^{tm1.1(KOMP)Vlcg}/2J	decreased circulating creatinine level	J:211773
	decreased total body fat amount	J:211773
	increased heart weight	J:211773
	increased lean body mass	J:211773
Cmtr2^{tm1.1(KOMP)Vlcg}/Cmtr2^{tm1.1(KOMP)Vlcg} B6N(Cg)-Cmtr2^{tm1.1(KOMP)Vlcg}/2J	abnormal embryo turning	J:211773
	embryonic growth retardation	J:211773
	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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