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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
MGI:2156052
45 phenotypes from 7 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Scn10atm2(cre)Jwo/Scn10a+
Slc17a6tm1Kldr/Slc17a6tm1Kldr
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		normal behavior/neurological phenotype J:167752
Slc17a6tm1.1Jder/Slc17a6tm1.1Jder
Emx1tm1(cre)Krj/Emx1+
B6.Cg-Emx1tm1(cre)Krj Slc17a6tm1.1Jder 		abnormal dendrite morphology J:192240
abnormal dendritic spine morphology J:192240
abnormal glutamate-mediated receptor currents J:192240
abnormal spatial learning J:192240
abnormal spatial reference memory J:192240
decreased body size J:192240
decreased synaptic glutamate release J:192240
increased exploration in new environment J:192240
increased paired-pulse ratio J:192240
reduced long-term depression J:192240
Slc17a6tm1.1Kldr/Slc17a6tm1.1Kldr
involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 		abnormal nervous system physiology J:116180
abnormal pre-Botzinger complex physiology J:116180
abnormal reflex J:116180
abnormal synaptic vesicle morphology J:116180
abnormal synaptic vesicle number J:116180
absence of AMPA-mediated synaptic currents J:116180
cyanosis J:116180
decreased birth body size J:116180
decreased fetal weight J:116180
enlarged third ventricle J:116180
hunched posture J:116180
neonatal lethality, complete penetrance J:116180
respiratory failure J:116180
Slc17a6tm1.1Lowl/Slc17a6tm1.1Lowl
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6J 		postnatal lethality, complete penetrance J:129860
Slc17a6tm1.2Jder/Slc17a6tm1.2Jder
involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 * C57BL/6J 		neonatal lethality, complete penetrance J:192240
Slc17a6tm1b(EUCOMM)Hmgu/Slc17a6tm1b(EUCOMM)Hmgu
C57BL/6N-Slc17a6tm1b(EUCOMM)Hmgu/H 		preweaning lethality, complete penetrance J:211773
Slc17a6tm1Kldr/Slc17a6tm1Kldr
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		no abnormal phenotype detected J:116180
Slc17a6tm1Kldr/Slc17a6tm1Kldr
Tg(PLAT-cre)116Sdu/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		excessive scratching J:167752
increased pruritus J:167752
increased thermal nociceptive threshold J:167752
Slc17a6tm1Kldr/Slc17a6tm1Kldr
Tg(Trpv1-icre)1Kldr/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		excessive scratching J:167752
increased thermal nociceptive threshold J:167752
Slc17a6tm1Kldr/Slc17a6tm1Kldr
Thtm1(cre)Te/Th+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal pain threshold J:167752
decreased chemically-elicited antinociception J:167752
excessive scratching J:167752
normal homeostasis/metabolism phenotype J:167752
increased pruritus J:167752
increased thermal nociceptive threshold J:167752
mixed cellular infiltration to dermis J:167752
skin lesions J:167752
thick epidermis J:167752
Slc17a6tm1Lex/Slc17a6+
involves: 129S5/SvEvBrd * C57BL/6 		abnormal conditioned taste aversion behavior J:116159
abnormal locomotor activation J:116159
abnormal miniature excitatory postsynaptic currents J:116159
abnormal pain threshold J:116159
Slc17a6tm1Lex/Slc17a6tm1Lex
involves: 129S5/SvEvBrd * C57BL/6 		abnormal CNS synaptic transmission J:116159
abnormal excitatory postsynaptic currents J:116159
abnormal motor capabilities/coordination/movement J:116159
decreased miniature excitatory postsynaptic current amplitude J:116159
decreased miniature excitatory postsynaptic current frequency J:116159
increased excitatory postsynaptic current amplitude J:116159
neonatal lethality, complete penetrance J:116159
respiratory failure J:116159
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory