Slc17a6^tm1.2Jder
Targeted Allele Detail

Summary

• Symbol: Slc17a6^tm1.2Jder
• Name: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6; targeted mutation 1.2, Jeffrey D Erickson
• MGI ID: MGI:5469841
• Synonyms: VGLUT2^delta
• Gene: Slc17a6 Location: Chr7:51271754-51320867 bp, + strand Genetic Position: Chr7, 32.78 cM, cytoband B4
• Alliance: Slc17a6^tm1.2Jder page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:192240
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: (C57BL/6J x 129)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre-mediated recombination removed the neo cassette and exon 2. Western blot analysis confirmed the absence of protein expression in whole brain vesicles. (J:192240)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc17a6 Mutation: 59 strains or lines available

References

• Original: J:192240 He H, et al., Neurodevelopmental role for VGLUT2 in pyramidal neuron plasticity, dendritic refinement, and in spatial learning. J Neurosci. 2012 Nov 7;32(45):15886-901
• All: 1 reference(s)