Tg(Trpv1-icre)1Kldr
Transgene Detail

Summary

• Symbol: Tg(Trpv1-icre)1Kldr
• Name: transgene insertion 1, Klas Kullander
• MGI ID: MGI:4880764
• Synonyms: TRPV1-Cre
• Transgene: Tg(Trpv1-icre)1Kldr Location: unknown
• Alliance: Tg(Trpv1-icre)1Kldr page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Trpv1-icre)1Kldr expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Trpv1 (MGI:1341787)

• Mutation details: A cassette containing codon improved cre (icre) and an FRT-flanked ampicillin resistance gene was inserted at the ATG site in the first exon in the Trpv1 gene in BAC RP23-292B23 containing the entire Trpv1 locus. The ampicillin gene was removed from the BAC construct by Flp expression. The purified BAC was microinjected into pronuclei of mouse oocytes. (J:167752)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Trpv1 (mouse) Summary of all recombinase alleles driven by Trpv1. Alliance mouse Trpv1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:167752 Lagerstrom MC, et al., VGLUT2-dependent sensory neurons in the TRPV1 population regulate pain and itch. Neuron. 2010 Nov 4;68(3):529-42
• All: 5 reference(s)