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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Trpv1-icre)1Kldr
transgene insertion 1, Klas Kullander
MGI:4880764
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Slc17a6tm1Kldr/Slc17a6tm1Kldr
Tg(Trpv1-icre)1Kldr/0 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:4887828


Genotype
MGI:4887828
cn1
Allelic
Composition		 Slc17a6tm1Kldr/Slc17a6tm1Kldr
Tg(Trpv1-icre)1Kldr/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc17a6tm1Kldr mutation (1 available); any Slc17a6 mutation (59 available)
Tg(Trpv1-icre)1Kldr mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
excessive scratching ( J:167752 )
• scratching behavior is significantly elevated compared to controls
increased thermal nociceptive threshold ( J:167752 )
• mice show decreased thermal pain sensitivity, but mechanical pain and inflammatory pain sensitivities are not different from control




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory