Marveld1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Marveld1
MARVEL (membrane-associating) domain containing 1
MGI:2147570

24 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Marveld1^tm1.1Liy/Marveld1^tm1.1Liy Tg(GFAP-cre)25Mes/0 involves: C57BL/6J * FVB/N	abnormal cerebellar granule cell migration	J:279065
	abnormal cerebellar Purkinje cell layer	J:279065
	abnormal CNS glial cell morphology	J:279065
	abnormal Purkinje cell dendrite morphology	J:279065
Marveld1^tm1.1Liy/Marveld1^tm1.1Liy Tg(Nes-cre)1Kln/0 involves: C57BL/6 * C57BL/6J * SJL	abnormal cerebellar granule cell migration	J:279065
	abnormal CNS glial cell morphology	J:279065
	abnormal Purkinje cell dendrite morphology	J:279065
	abnormal Purkinje cell morphology	J:279065
Marveld1^tm1.2Liy/Marveld1^tm1.2Liy involves: C57BL/6J	abnormal Bergmann glial cell morphology	J:279065
	abnormal cerebellar granule cell migration	J:279065
	abnormal cerebellar layer morphology	J:279065
	abnormal cerebellar Purkinje cell layer	J:279065
	abnormal CNS glial cell morphology	J:279065
	abnormal dendrite morphology	J:279065
	abnormal gait	J:279065
	abnormal locomotor activation	J:279065
	abnormal neuronal migration	J:279065
	abnormal posture	J:279065
	abnormal Purkinje cell dendrite morphology	J:279065
	abnormal Purkinje cell morphology	J:279065
	abnormal stratification in cerebral cortex	J:279065
	abnormal synapse morphology	J:279065
	decreased neuron number	J:279065
	impaired coordination	J:279065
	impaired spatial learning	J:279065
	impaired swimming	J:279065
	increased neuron apoptosis	J:279065
	increased thermal nociceptive threshold	J:279065
	neuron degeneration	J:279065
	Purkinje cell degeneration	J:279065
	short stride length	J:279065
	thin external granule cell layer	J:279065

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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