Cblb Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cblb
Casitas B-lineage lymphoma b
MGI:2146430

16 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cbl^tm2Hua/Cbl^tm2Hua Cblb^tm1Hua/Cblb^tm1Hua Tg(Lck-cre)I57Jxm/0 involves: 129P2/OlaHsd * C57BL/6 * ICR	abnormal blood vessel morphology	J:80427
	abnormal immune system physiology	J:80427
	abnormal T cell morphology	J:80427
	decreased body weight	J:80427
	dermatitis	J:80427
	enlarged spleen	J:80427
	extramedullary hematopoiesis	J:80427
	increased T cell proliferation	J:80427
	liver fibrosis	J:80427
	premature death	J:80427
Cblb^tm1Hua/Cblb^tm1Hua Ubash3b^tm1Jni/Ubash3b^tm1Jni Ubash3a^tm1Jni/Ubash3a^tm1Jni Not Specified	increased susceptibility to experimental autoimmune encephalomyelitis	J:89761
	increased T cell proliferation	J:89761
Cblb^tm1Pngr/Cblb^tm1Pngr Itk^tm1Litt/Itk^tm1Litt B6.129-Itk^tm1Litt Cblb^tm1Pngr	abnormal T cell morphology	J:141390
	abnormal T-helper 2 cell differentiation	J:141390
	decreased interleukin-2 secretion	J:141390
	decreased T cell number	J:141390
	normal immune system phenotype	J:141390
Cblb^tm1Pngr/Cblb^tm1Pngr Vav1^tm1Tyb/Vav1^tm1Tyb Was^tm1Sbs/Was^tm1Sbs involves: 129P2/OlaHsd * 129S2/SvPas * 129S6/SvEvTac	abnormal T cell physiology	J:79550
Cblb^tm1Pngr/Cblb^tm1Pngr Was^tm1Sbs/Was^tm1Sbs Not Specified	abnormal T cell physiology	J:79550

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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