Prmt9 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prmt9
protein arginine methyltransferase 9
MGI:2142651

26 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prmt9^em1(IMPC)J/Prmt9^em1(IMPC)J C57BL/6NJ-Prmt9^em1(IMPC)J/Mmjax	abnormal auditory brainstem response	J:211773
	cataract	J:211773
	improved glucose tolerance	J:211773
	increased grip strength	J:211773
	increased mean corpuscular hemoglobin	J:211773
	increased mean corpuscular volume	J:211773
Prmt9^em1.1Sqiu/Prmt9^em1.1Sqiu B6(C)-Prmt9^em1.1Sqiu	decreased body size	J:360860
	decreased body weight	J:360860
	postnatal lethality, incomplete penetrance	J:360860
Prmt9^em1Cya/Prmt9^em1Cya Lyz2^tm1(cre)Ifo/Lyz2⁺ involves: 129P2/OlaHsd * C57BL/6N	decreased susceptibility to viral infection	J:328263
	increased circulating interferon-beta level	J:328263
	increased interferon-beta secretion	J:328263
Prmt9^em1Sqiu/Prmt9^em1Sqiu Emx1^tm1(cre)Krj/Emx1⁺ B6.Cg-Emx1^tm1(cre)Krj Prmt9^em1Sqiu	abnormal excitatory postsynaptic potential	J:360860
	abnormal excitatory synapse morphology	J:360860
	abnormal glutamate-mediated receptor currents	J:360860
	abnormal long-term spatial reference memory	J:360860
	decreased CNS synapse formation	J:360860
	decreased dendritic spine density	J:360860
	decreased excitatory postsynaptic current amplitude	J:360860
	decreased excitatory postsynaptic current frequency	J:360860
	impaired contextual conditioning behavior	J:360860
	impaired cued conditioning behavior	J:360860
	impaired spatial learning	J:360860
	impaired spatial memory extinction	J:360860
	reduced long-term depression	J:360860
	reduced long-term potentiation	J:360860

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24