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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Dbn1
drebrin 1
MGI:1931838
64 phenotypes from 6 alleles in 15 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Dbn1em1(IMPC)Bay/Dbn1em1(IMPC)Bay
C57BL/6N-Dbn1em1(IMPC)Bay/Bay
abnormal coat appearance J:211773
abnormal eye anterior chamber depth J:211773
hyperactivity J:211773
increased cornea thickness J:211773
Dbn1em2(IMPC)Mbp/Dbn1em2(IMPC)Mbp
C57BL/6N-Dbn1em2(IMPC)Mbp/Ucd
abnormal allantois morphology J:211773
abnormal chorioallantoic fusion J:211773
abnormal embryo turning J:211773
Dbn1tm1.1Lbc/Dbn1+
B6.Cg-Dbn1tm1.1Lbc
abnormal dendritic spine morphology J:224553
Dbn1tm1.1Lbc/Dbn1tm1.1Lbc
B6.Cg-Dbn1tm1.1Lbc
abnormal dendritic spine morphology J:224553
abnormal hippocampus morphology J:224553
impaired synaptic plasticity J:224553
Dbn1tm1.1Shira/Dbn1tm1.1Shira
either: C57BL/6-Dbn1tm1.1Shira or (involves: C57BL/6CrSlc * C57BL/6J * FVB/N)
impaired cued conditioning behavior J:158208
Dbn1tm1a(KOMP)Wtsi/Dbn1+
C57BL/6N-Dbn1tm1a(KOMP)Wtsi/Wtsi
increased leukocyte cell number J:211773
Dbn1tm1a(KOMP)Wtsi/Dbn1tm1a(KOMP)Wtsi
C57BL/6N-Dbn1tm1a(KOMP)Wtsi/Wtsi
decreased body weight J:175295
decreased circulating alanine transaminase level J:175295
decreased circulating aspartate transaminase level J:175295
decreased circulating calcium level J:175295
decreased circulating cholesterol level J:175295
decreased circulating fructosamine level J:175295
decreased circulating HDL cholesterol level J:175295
decreased circulating LDL cholesterol level J:175295
decreased circulating serum albumin level J:175295
decreased circulating total protein level J:175295
decreased mean corpuscular volume J:175295
decreased total body fat amount J:175295
increased circulating chloride level J:175295
preweaning lethality, incomplete penetrance J:211773
Dbn1tm1b(KOMP)Wtsi/Dbn1+
C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Bay
decreased circulating cholesterol level J:211773
decreased circulating serum albumin level J:211773
decreased vertical activity J:211773
enlarged heart J:211773
unresponsive to tactile stimuli J:211773
Dbn1tm1b(KOMP)Wtsi/Dbn1+
C57BL/6N-Dbn1tm1b(KOMP)Wtsi/H
abnormal vertebrae morphology J:211773
Dbn1tm1b(KOMP)Wtsi/Dbn1+
C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Ics
decreased grip strength J:211773
decreased total retina thickness J:211773
Dbn1tm1b(KOMP)Wtsi/Dbn1+
C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Ieg
decreased mean platelet volume J:211773
increased red blood cell distribution width J:211773
Dbn1tm1b(KOMP)Wtsi/Dbn1+
C57BL/6N-Dbn1tm1b(KOMP)Wtsi/J
decreased circulating free fatty acids level J:211773
decreased circulating serum albumin level J:211773
increased lean body mass J:211773
Dbn1tm1b(KOMP)Wtsi/Dbn1+
C57BL/6N-Dbn1tm1b(KOMP)Wtsi/MbpMmucd
decreased total body fat amount J:211773
increased bone mineral content J:211773
increased prepulse inhibition J:211773
microcephaly J:211773
syndactyly J:211773
Dbn1tm1b(KOMP)Wtsi/Dbn1+
C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Rbrc
increased circulating alkaline phosphatase level J:211773
increased exploration in new environment J:211773
Dbn1tm1b(KOMP)Wtsi/Dbn1+
C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Ucd
decreased total body fat amount J:211773
increased bone mineral content J:211773
increased circulating phosphate level J:211773
increased lean body mass J:211773
Dbn1tm1b(KOMP)Wtsi/Dbn1+
C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Wtsi
increased CD8-positive, alpha-beta T cell number J:211773
increased circulating chloride level J:211773
increased circulating creatinine level J:211773
increased circulating magnesium level J:211773
Dbn1tm1b(KOMP)Wtsi/Dbn1+
C57BL/6NCrl-Dbn1tm1b(KOMP)Wtsi/Wtsi
abnormal heart morphology J:211773
abnormal liver morphology J:211773
enlarged heart J:211773
increased fasting circulating glucose level J:211773
Dbn1tm1b(KOMP)Wtsi/Dbn1tm1b(KOMP)Wtsi
C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Bay
abnormal embryo size J:211773
preweaning lethality, incomplete penetrance J:211773
unresponsive to tactile stimuli J:211773
Dbn1tm1b(KOMP)Wtsi/Dbn1tm1b(KOMP)Wtsi
C57BL/6N-Dbn1tm1b(KOMP)Wtsi/H
preweaning lethality, incomplete penetrance J:211773
Dbn1tm1b(KOMP)Wtsi/Dbn1tm1b(KOMP)Wtsi
C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Ics
preweaning lethality, complete penetrance J:211773
Dbn1tm1b(KOMP)Wtsi/Dbn1tm1b(KOMP)Wtsi
C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Ieg
preweaning lethality, complete penetrance J:211773
Dbn1tm1b(KOMP)Wtsi/Dbn1tm1b(KOMP)Wtsi
C57BL/6N-Dbn1tm1b(KOMP)Wtsi/J
preweaning lethality, incomplete penetrance J:211773
Dbn1tm1b(KOMP)Wtsi/Dbn1tm1b(KOMP)Wtsi
C57BL/6N-Dbn1tm1b(KOMP)Wtsi/MbpMmucd
microcephaly J:211773
preweaning lethality, complete penetrance J:211773
preweaning lethality, incomplete penetrance J:211773
syndactyly J:211773
Dbn1tm1b(KOMP)Wtsi/Dbn1tm1b(KOMP)Wtsi
C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Rbrc
preweaning lethality, complete penetrance J:211773
Dbn1tm1b(KOMP)Wtsi/Dbn1tm1b(KOMP)Wtsi
C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Ucd
preweaning lethality, complete penetrance J:211773
preweaning lethality, incomplete penetrance J:211773
Dbn1tm1b(KOMP)Wtsi/Dbn1tm1b(KOMP)Wtsi
C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Wtsi
abnormal brachial plexus formation J:239583
abnormal brain internal capsule morphology J:239583
abnormal brain white matter morphology J:239583
abnormal cervical rib J:239583
abnormal forebrain morphology J:239583
abnormal hypoglossal canal morphology J:239583
abnormal telencephalon morphology J:239583
abnormal Wolffian duct connection J:239583
absent hypoglossal canal J:239583
absent hypoglossal nerve J:239583
dilated liver sinusoidal space J:239583
preweaning lethality, incomplete penetrance J:211773
thin hypoglossal nerve J:239583
Dbn1tm1b(KOMP)Wtsi/Dbn1tm1b(KOMP)Wtsi
C57BL/6NCrl-Dbn1tm1b(KOMP)Wtsi/Wtsi
no spontaneous movement J:211773
preweaning lethality, complete penetrance J:211773

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory