64 phenotypes from 7 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cd79atm1(cre)Reth/Cd79a+ Huwe1tm1.1Mak/Y B6.Cg-Cd79atm1(cre)Reth Huwe1tm1.1Mak	abnormal B cell differentiation	J:181705
	abnormal class switch recombination	J:181705
	abnormal humoral immune response	J:181705
	absent B-1a cells	J:181705
	decreased B cell proliferation	J:181705
	decreased follicular B cell number	J:181705
	decreased IgA level	J:181705
	decreased IgG1 level	J:181705
	decreased IgG2a level	J:181705
	decreased IgG3 level	J:181705
	decreased IgM level	J:181705
	decreased marginal zone B cell number	J:181705
	decreased mature B cell number	J:181705
	decreased pre-B cell number	J:181705
	decreased transitional stage B cell number	J:181705
	increased B cell apoptosis	J:181705
	increased susceptibility to Riboviria infection	J:181705
Huwe1Gt(DC0732)Wtsi/Y chimera involves: 129P2/OlaHsd	embryonic growth retardation	J:160967
	embryonic lethality during organogenesis, incomplete penetrance	J:160967
	incomplete embryo turning	J:160967
	microcephaly	J:160967
	small heart	J:160967
Huwe1Gt(P036B01)Wrst/Y chimera involves: 129S6/SvEvTac * C57BL/6	abnormal endoderm development	J:160967
Huwe1Gt(P125E01)Wrst/Y chimera involves: 129S2/SvPas	abnormal developmental patterning	J:160967
	abnormal gastrulation	J:160967
Huwe1tm1.2Mak/Y involves: 129P2/OlaHsd * BALB/cJ * C57BL/6 * SJL	decreased embryo size	J:181705
	decreased somite size	J:181705
	embryonic lethality during organogenesis, complete penetrance	J:181705
	enlarged heart	J:181705
Huwe1tm1Alas/Y Tg(Nes-cre)1Kag/0 involves: 129S7/SvEvBrd	abnormal brain morphology	J:152966
	abnormal cerebral cortex morphology	J:152966
	abnormal dentate gyrus morphology	J:152966
	abnormal neuronal precursor proliferation	J:152966
	abnormal stratification in cerebral cortex	J:152966
	decreased brain size	J:152966
	increased neuronal precursor cell number	J:152966
	neonatal lethality	J:152966
	small cerebellum	J:152966
	thin cerebral cortex	J:152966
Huwe1tm1Alas/Y Tg(Prm-cre)58Og/0 involves: 129S4/SvJae * 129S7/SvEvBrd	normal reproductive system phenotype	J:323709
Huwe1tm1Alas/Y Tg(Spo11-cre)1Rsw/0 involves: 129S7/SvEvBrd	abnormal spermatocyte morphology	J:323709
	normal reproductive system phenotype	J:323709
Huwe1tm1Alas/Y Tg(Stra8-icre)1Reb/0 involves: 129S7/SvEvBrd * C57BL/6 * FVB/NJ	abnormal caput epididymis morphology	J:323709
	abnormal male germ cell physiology	J:323709
	abnormal male meiosis	J:323709
	abnormal spermatocyte morphology	J:323709
	abnormal spermatogonia morphology	J:323709
	arrest of spermatogenesis	J:323709
	decreased male germ cell number	J:323709
	decreased testis weight	J:323709
	increased male germ cell apoptosis	J:323709
	increased testis apoptosis	J:323709
	male infertility	J:323709
	oligozoospermia	J:323709
	small testis	J:323709
Huwe1tm1Wgu/Y involves: C57BL/6J	no abnormal phenotype detected	J:182446
Huwe1tm1Wgu/Huwe1tm1Wgu involves: C57BL/6J	no abnormal phenotype detected	J:182446
Huwe1tm1Wgu/Y Tg(Ins2-cre)23Herr/0 involves: C57BL/6J * CBA/J	abnormal urinary bladder morphology	J:182446
	decreased body weight	J:182446
	decreased circulating insulin level	J:182446
	decreased pancreatic beta cell number	J:182446
	disorganized pancreatic islets	J:182446
	hyperglycemia	J:182446
	impaired glucose tolerance	J:182446
	increased circulating glucose level	J:182446
	polyuria	J:182446
	premature death	J:182446