Mapk8ip2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mapk8ip2
mitogen-activated protein kinase 8 interacting protein 2
MGI:1926555

21 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mapk8ip2^tm1.1Gol/Mapk8ip2^tm1.1Gol 129S/SvEv-Mapk8ip2^tm1.1Gol	abnormal excitatory postsynaptic currents	J:166700
	abnormal miniature excitatory postsynaptic currents	J:166700
	abnormal Purkinje cell dendrite morphology	J:166700
	abnormal Purkinje cell morphology	J:166700
	abnormal social investigation	J:166700
	normal behavior/neurological phenotype	J:166700
	decreased anxiety-related response	J:166700
	decreased exploration in new environment	J:166700
	decreased grip strength	J:166700
	decreased synaptic glutamate release	J:166700
	enhanced NMDA-mediated synaptic currents	J:166700
	impaired coordination	J:166700
	normal nervous system phenotype	J:166700
	reduced AMPA-mediated synaptic currents	J:166700
	reduced fertility	J:166700
	normal taste/olfaction phenotype	J:166700
	thin cerebellar molecular layer	J:166700
	normal vision/eye phenotype	J:166700
Mapk8ip2^tm1Rjd/Mapk8ip2^tm1Rjd involves: 129X1/SvJ * C57BL/6	abnormal NMDA-mediated synaptic currents	J:125318
	decreased body size	J:125318
	male infertility	J:125318

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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