Mapk8ip2^tm1.1Gol
Targeted Allele Detail

Summary

• Symbol: Mapk8ip2^tm1.1Gol
• Name: mitogen-activated protein kinase 8 interacting protein 2; targeted mutation 1.1, Mitchell Goldfarb
• MGI ID: MGI:4867721
• Gene: Mapk8ip2 Location: Chr15:89338114-89346650 bp, + strand Genetic Position: Chr15, 44.92 cM
• Alliance: Mapk8ip2^tm1.1Gol page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:166700
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre mediated recombination removed exons 3 through 8. The absence of transcript expression was confirmed by RT-PCR on brain extracts. (J:166700)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mapk8ip2 Mutation: 26 strains or lines available

References

• Original: J:166700 Giza J, et al., Behavioral and cerebellar transmission deficits in mice lacking the autism-linked gene islet brain-2. J Neurosci. 2010 Nov 3;30(44):14805-16
• All: 2 reference(s)