56 phenotypes from 5 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Orai1Gt(XL922)Byg/Orai1+ involves: 129P2/OlaHsd * C57BL/6 * DBA/2	abnormal mast cell physiology	J:130479
	decreased interferon-gamma secretion	J:130479
	decreased leukotriene level	J:130479
Orai1Gt(XL922)Byg/Orai1Gt(XL922)Byg involves: 129P2/OlaHsd	abnormal neuron physiology	J:159604
Orai1Gt(XL922)Byg/Orai1Gt(XL922)Byg involves: 129P2/OlaHsd * C57BL/6 * DBA/2	abnormal mast cell physiology	J:130479
	decreased body size	J:130479
	decreased interferon-gamma secretion	J:130479
	decreased interleukin-2 secretion	J:130479
	decreased leukotriene level	J:130479
	decreased susceptibility to type I hypersensitivity reaction	J:130479
	normal mortality/aging	J:130479
Orai1Gt(XL922)Byg/Orai1Gt(XL922)Byg involves: 129P2/OlaHsd * ICR	abnormal calcium ion homeostasis	J:315408
	abnormal cauda epididymis morphology	J:315408
	abnormal ectoplasmic specialization morphology	J:315408
	abnormal Golgi apparatus morphology	J:315408
	abnormal male germ cell physiology	J:315408
	abnormal seminiferous tubule epithelium morphology	J:315408
	abnormal Sertoli cell barrier morphology	J:315408
	abnormal Sertoli cell morphology	J:315408
	abnormal sperm head morphology	J:315408
	abnormal spermatid morphology	J:315408
	abnormal spermatocyte morphology	J:315408
	abnormal spermatogenesis	J:315408
	abnormal spermiogenesis	J:315408
	asthenozoospermia	J:315408
	decreased body weight	J:315408
	decreased sperm progressive motility	J:315408
	decreased testis weight	J:315408
	dilated mitochondrion	J:315408
	dilated seminiferous tubule	J:315408
	male infertility	J:315408
	multinucleated giant male germ cells	J:315408
	oligozoospermia	J:315408
	normal reproductive system phenotype	J:315408
	seminiferous tubule degeneration	J:315408
Orai1tm1.1Hjm/Orai1tm1.1Hjm Tg(Cd4-cre)1Cwi/0 B6.Cg-Orai1tm1.1Hjm Tg(Cd4-cre)1Cwi	abnormal T cell physiology	J:241365
Orai1tm1b(EUCOMM)Hmgu/Orai1+ C57BL/6N-Orai1tm1b(EUCOMM)Hmgu/Bay	abnormal sinus arrhythmia	J:211773
	unresponsive to tactile stimuli	J:211773
Orai1tm1b(EUCOMM)Hmgu/Orai1tm1b(EUCOMM)Hmgu C57BL/6N-Orai1tm1b(EUCOMM)Hmgu/Bay	abnormal embryo size	J:211773
	preweaning lethality, complete penetrance	J:211773
	unresponsive to tactile stimuli	J:211773
Orai1tm1Fesk/Orai1tm1Fesk C57BL/6-Orai1tm1Fesk	abnormal platelet activation	J:144861
	decreased platelet calcium level	J:144861
	neonatal lethality, complete penetrance	J:144861
Orai1tm1Rao/Orai1+ C57BL/6-Orai1tm1Rao	abnormal B cell activation	J:139730
	abnormal T cell activation	J:139730
Orai1tm1Rao/Orai1tm1Rao C57BL/6-Orai1tm1Rao	abnormal cell physiology	J:139730
	perinatal lethality, complete penetrance	J:139730
	prenatal lethality, incomplete penetrance	J:139730
Orai1tm1Rao/Orai1tm1Rao involves: C57BL/6NTac * ICR	abnormal B cell activation	J:139730
	abnormal cell-mediated immunity	J:139730
	abnormal cytokine secretion	J:139730
	abnormal mast cell physiology	J:139730
	abnormal T cell activation	J:139730
	abnormal thymocyte activation	J:139730
	alopecia	J:139730
	blepharitis	J:139730
	decreased body weight	J:139730
	decreased interferon-gamma secretion	J:139730
	decreased interleukin-2 secretion	J:139730
	decreased interleukin-4 secretion	J:139730
	decreased interleukin-10 secretion	J:139730
	decreased survivor rate	J:139730
	perinatal lethality, incomplete penetrance	J:139730
	short vibrissae	J:139730
	thin skin	J:139730