90 phenotypes from 7 alleles in 13 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ehmt1Tg(Tyr)2265COve/Ehmt1Tg(Tyr)2265COve FVB/N-Ehmt1Tg(Tyr)2265COve	embryonic lethality during organogenesis, complete penetrance	J:175597
Ehmt1tm1.1Tara/Ehmt1tm1.1Tara Myf5tm3(cre)Sor/Myf5+ involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6	decreased brown fat cell size	J:207678
	decreased brown fat lipid droplet number	J:207678
	decreased interscapular fat pad weight	J:207678
Ehmt1tm1.1Tara/Ehmt1tm1.1Tara Tg(Adipoq-cre)1Evdr/0 involves: 129P2/OlaHsd * FVB/NJ	abnormal brown adipose tissue physiology	J:207678
	abnormal liver morphology	J:207678
	abnormal oxygen consumption	J:207678
	decreased body temperature	J:207678
	decreased fatty acid oxidation	J:207678
	impaired adaptive thermogenesis	J:207678
	impaired glucose tolerance	J:207678
	increased body weight	J:207678
	increased brown fat cell lipid droplet size	J:207678
	increased circulating free fatty acids level	J:207678
	increased circulating glucose level	J:207678
	increased circulating insulin level	J:207678
	increased epididymal fat pad weight	J:207678
	increased interscapular fat pad weight	J:207678
	increased liver triglyceride level	J:207678
	increased white fat cell lipid droplet size	J:207678
	insulin resistance	J:207678
Ehmt1tm1.1Tara/Ehmt1tm1.1Tara Tg(Camk2a-cre)2Gsc/0 involves: 129P2/OlaHsd * C57BL/6 * FVB/N	abnormal liquid preference	J:155739
	abnormal motor coordination/balance	J:155739
	decreased anxiety-related response	J:155739
	decreased exploration in new environment	J:155739
	decreased locomotor activity	J:155739
	decreased vertical activity	J:155739
	impaired behavioral response to xenobiotic	J:155739
	impaired contextual conditioning behavior	J:155739
	impaired cued conditioning behavior	J:155739
	normal nervous system phenotype	J:155739
	obese	J:155739
Ehmt1tm1.2Tara/Ehmt1+ Tg(CMV-cre)1Cgn/0 involves: 129P2/OlaHsd * BALB/cJ * C57BL/6	decreased exploration in new environment	J:155739
	decreased locomotor activity	J:155739
	decreased vertical activity	J:155739
Ehmt1tm1b(EUCOMM)Hmgu/Ehmt1+ C57BL/6N-Ehmt1tm1b(EUCOMM)Hmgu/Nju	abnormal behavior	J:211773
	abnormal iris morphology	J:211773
	abnormal optic disk morphology	J:211773
	abnormal retina blood vessel morphology	J:211773
	abnormal retina vasculature morphology	J:211773
	corneal opacity	J:211773
	decreased blood urea nitrogen level	J:211773
	decreased circulating creatinine level	J:211773
	decreased circulating serum albumin level	J:211773
	decreased exploration in new environment	J:211773
	decreased locomotor activity	J:211773
	impaired pupillary reflex	J:211773
	increased anxiety-related response	J:211773
	increased grip strength	J:211773
	increased lean body mass	J:211773
	increased mean platelet volume	J:211773
	increased neutrophil cell number	J:211773
	increased thigmotaxis	J:211773
	irregularly shaped pupil	J:211773
	persistence of hyaloid vascular system	J:211773
Ehmt1tm1b(EUCOMM)Hmgu/Ehmt1+ C57BL/6N-Ehmt1tm1b(EUCOMM)Hmgu/Wtsi	increased circulating cholesterol level	J:211773
	increased circulating LDL cholesterol level	J:211773
Ehmt1tm1b(EUCOMM)Hmgu/Ehmt1tm1b(EUCOMM)Hmgu C57BL/6N-Ehmt1tm1b(EUCOMM)Hmgu/Nju	preweaning lethality, complete penetrance	J:211773
Ehmt1tm1b(EUCOMM)Hmgu/Ehmt1tm1b(EUCOMM)Hmgu C57BL/6N-Ehmt1tm1b(EUCOMM)Hmgu/Wtsi	preweaning lethality, complete penetrance	J:211773
Ehmt1tm1Bzhu/Ehmt1tm1Bzhu involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal epigenetic regulation of gene expression	J:219788
	abnormal metopic suture morphology	J:219788
	abnormal nasal bone morphology	J:219788
	abnormal suckling behavior	J:219788
	absent gastric milk in neonates	J:219788
	decreased birth body size	J:219788
	decreased embryo weight	J:219788
	decreased fetal weight	J:219788
	decreased survivor rate	J:219788
	delayed intramembranous bone ossification	J:219788
	malocclusion	J:219788
	postnatal growth retardation	J:219788
	postnatal lethality, incomplete penetrance	J:219788
	prenatal growth retardation	J:219788
Ehmt1tm1Yshk/Ehmt1+ involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj	abnormal associative learning	J:192316
	abnormal dendrite morphology	J:192316
	abnormal dendritic spine morphology	J:192316
	abnormal hippocampus pyramidal cell morphology	J:192316
	abnormal miniature excitatory postsynaptic currents	J:192316
	abnormal object recognition memory	J:192316
	abnormal response to novel object	J:157021, J:192316
	abnormal sensory capabilities/reflexes/nociception	J:192316
	abnormal social investigation	J:157021
	abnormal social/conspecific interaction behavior	J:157021
	decreased anxiety-related response	J:157021
	decreased exploration in new environment	J:157021
	decreased locomotor activity	J:157021
	decreased vertical activity	J:157021
	enhanced paired-pulse facilitation	J:192316
	impaired contextual conditioning behavior	J:192316
	impaired cued conditioning behavior	J:192316
	impaired synaptic plasticity	J:192316
	increased anxiety-related response	J:157021
	increased startle reflex	J:192316
Ehmt1tm1Yshk/Ehmt1tm1Yshk involves: C57BL/6NCrlj * CBA/JNCrlj	embryonic growth retardation	J:97244
	embryonic lethality during organogenesis, complete penetrance	J:97244
	incomplete somite formation	J:97244
	open neural tube	J:97244
Ehmt1tm2Yshk/Ehmt1tm2Yshk Not Specified	no abnormal phenotype detected	J:204470
Ehmt1tm2Yshk/Ehmt1tm2Yshk Nkx2-5tm1(cre)Rjs/Nkx2-5+ involves: 129S7/SvEvBrd	abnormal mitral valve cusp morphology	J:204470
	absent tricuspid valve cusps	J:204470
	atrioventricular septal defect	J:204470
	decreased atrioventricular cushion size	J:204470
	neonatal lethality, incomplete penetrance	J:204470
	premature death	J:204470
Ehmt1tm2Yshk/Ehmt1tm2Yshk Tg(Myh6-cre)2182Mds/0 involves: FVB/N	no abnormal phenotype detected	J:204470