Il33 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Il33
interleukin 33
MGI:1924375

39 phenotypes from 6 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Il33^{Gt(IST10946B6)Tigm}/Il33^{Gt(IST10946B6)Tigm} C57BL/6-Il33^{Gt(IST10946B6)Tigm}	normal mortality/aging	J:183103
Il33^{tm1(KOMP)Vlcg}/Il33^{tm1(KOMP)Vlcg} C57BL/6-Il33^{tm1(KOMP)Vlcg}	abnormal autophagy	J:232676, J:251814
	abnormal double-strand DNA break repair	J:251814
	abnormal habituation to a new environment	J:251814
	abnormal neuron morphology	J:251814
	abnormal ovarian follicle morphology	J:232676
	abnormal ovary morphology	J:232676
	abnormal ovary physiology	J:232676
	decreased corpora lutea number	J:232676
	decreased superovulation rate	J:232676
	early reproductive senescence	J:232676
	hippocampal neuron degeneration	J:251814
	impaired macrophage chemotaxis	J:232676
	impaired ovarian folliculogenesis	J:232676
	impaired passive avoidance behavior	J:251814
	increased locomotor activity	J:251814
	increased vertical activity	J:251814
	neurodegeneration	J:251814
	tau protein deposits	J:251814
Il33^{tm1.1(KOMP)Vlcg}/Il33^{tm1.1(KOMP)Vlcg} C57BL/6N-Il33^{tm1.1(KOMP)Vlcg}/Ucd	abnormal coat/ hair morphology	J:211773
	decreased heart rate	J:211773
	prolonged RR interval	J:211773
Il33^tm1Aki/Il33^tm1Aki involves: 129X1/SvJ * C57BL/6	abnormal T-helper 2 physiology	J:182160
	decreased eosinophil cell number	J:182160
	decreased IgE level	J:182160
	decreased respiratory mucosa goblet cell number	J:182160
	normal immune system phenotype	J:182160
	increased susceptibility to parasitic infection	J:182160
Il33^tm1Amgn/Il33^tm1Amgn B6.129-Il33^tm1Amgn	abnormal immune cell physiology	J:192531
	decreased lymphocyte cell number	J:192531
	increased susceptibility to parasitic infection	J:192531
Il33^tm1Snak/Il33^tm1Snak involves: C57BL/6 * CBA	decreased airway responsiveness	J:165513
	decreased inflammatory response	J:165513
	decreased interleukin-1 alpha secretion	J:165513
	decreased interleukin-1 beta secretion	J:165513
	decreased interleukin-6 secretion	J:165513
	decreased susceptibility to endotoxin shock	J:165513
	decreased susceptibility to xenobiotic induced morbidity/mortality	J:165513
	normal immune system phenotype	J:165513
	increased susceptibility to induced colitis	J:165513
	lung inflammation	J:165513

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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