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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Msi2
musashi RNA-binding protein 2
MGI:1923876
59 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Msi2em1(IMPC)Mbp/Msi2em1(IMPC)Mbp
C57BL/6N-Msi2em1(IMPC)Mbp/MbpMmucd 		abnormal brain morphology J:211773
abnormal gait J:211773
abnormal kidney morphology J:211773
abnormal liver morphology J:211773
abnormal retina morphology J:211773
abnormal spleen morphology J:211773
decreased body length J:211773
decreased brain size J:211773
decreased brain weight J:211773
decreased exploration in new environment J:211773
decreased fasting circulating glucose level J:211773
decreased lean body mass J:211773
decreased leukocyte cell number J:211773
decreased liver weight J:211773
decreased locomotor activity J:211773
decreased lymphocyte cell number J:211773
decreased neutrophil cell number J:211773
decreased spleen weight J:211773
decreased startle reflex J:211773
eye hemorrhage J:211773
increased circulating alkaline phosphatase level J:211773
increased circulating triglyceride level J:211773
increased mean platelet volume J:211773
increased total body fat amount J:211773
persistence of hyaloid vascular system J:211773
small kidney J:211773
small liver J:211773
small spleen J:211773
Msi2Gt(Ayu21-T2)Imeg/Msi2Gt(Ayu21-T2)Imeg
involves: C57BL/6 * CBA/JNCrlj 		decreased body size J:162770
decreased hematopoietic stem cell number J:162770
decreased tumor growth/size J:162770
postnatal lethality J:162770
Msi2Gt(E035H03)Wrst/Msi2Gt(E035H03)Wrst
B6.129P2-Msi2Gt(E035H03)Wrst 		abnormal bone marrow cell morphology/development J:174870
abnormal common lymphocyte progenitor cell morphology J:174870
abnormal fertility/fecundity J:174870
abnormal hematopoietic stem cell physiology J:174870
abnormal myeloid leukocyte morphology J:174870
decreased B cell number J:174870
decreased body weight J:174870
decreased CD4-positive, alpha-beta T cell number J:174870
decreased CD8-positive, alpha-beta T cell number J:174870
decreased common myeloid progenitor cell number J:174870
decreased DN2 thymocyte number J:174870
decreased DN3 thymocyte number J:174870
decreased double-negative T cell number J:174870
decreased double-positive T cell number J:174870
decreased erythrocyte cell number J:174870
decreased granulocyte number J:174870
decreased hematopoietic stem cell number J:174870
decreased immature B cell number J:174870
decreased leukocyte cell number J:174870
decreased macrophage cell number J:174870
decreased mature B cell number J:174870
decreased pre-B cell number J:174870
normal hematopoietic system phenotype J:174870
prenatal lethality, incomplete penetrance J:174870
small spleen J:174870
small thymus J:174870
spleen hypoplasia J:174870
thymus hypoplasia J:174870
Msi2tm1.1Cjl/Msi2tm1.1Cjl
Tg(Mx1-cre)1Cgn/0
involves: 129S4/SvJae * C57BL/6 * CBA 		abnormal hematopoietic stem cell physiology J:208349
decreased bone marrow cell number J:208349
decreased hematopoietic stem cell number J:208349
decreased spleen weight J:208349
normal immune system phenotype J:208349
spleen hypoplasia J:208349
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory