Pdxp Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
MGI:1919282

24 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pdxp^em1(IMPC)J/Pdxp^em1(IMPC)J C57BL/6NJ-Pdxp^em1(IMPC)J/Mmjax	abnormal bone structure	J:211773
	decreased bone mineral content	J:211773
	hyperactivity	J:211773
	increased lean body mass	J:211773
	increased leukocyte cell number	J:211773
Pdxp^tm1.1Ango/Pdxp^tm1.1Ango Tg(ACTA1-cre)79Jme/0 involves: C57BL/6J * SJL	increased grip strength	J:270551
Pdxp^tm1.1Ango/Pdxp^tm1.1Ango Tg(Nes-cre)1Kln/0 involves: C57BL/6J * SJL	decreased grip strength	J:270551
Pdxp^tm1.2Ango/Pdxp^tm1.2Ango involves: C57BL/6J	abnormal amino acid level	J:270551
	abnormal emotion/affect behavior	J:270551
	abnormal spatial reference memory	J:270551
	abnormal vitamin level	J:270551
	decreased glutamine level	J:270551
	decreased glycine level	J:270551
	decreased grip strength	J:270551
	decreased methionine level	J:270551
	decreased phenylalanine level	J:270551
	enhanced spatial learning	J:270551
	increased anxiety-related response	J:270551
	increased gamma-aminobutyric acid level	J:270551
	increased serine level	J:270551
	increased thigmotaxis	J:270551
	increased threonine level	J:270551
	normal mortality/aging	J:270551
	muscle weakness	J:270551
	normal reproductive system phenotype	J:270551

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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