Telo2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Telo2
telomere maintenance 2
MGI:1918968

7 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Telo2^em1(IMPC)J/Telo2⁺ C57BL/6NJ-Telo2^em1(IMPC)J/J	increased total body fat amount	J:211773
Telo2^em1(IMPC)J/Telo2^em1(IMPC)J C57BL/6NJ-Telo2^em1(IMPC)J/J	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773
Telo2^tm1.1Tdl/Telo2^tm1.1Tdl involves: 129P2/OlaHsd * C57BL/6J	embryonic lethality during organogenesis, complete penetrance	J:141633
Telo2^tm1Tdl/Telo2^tm1.1Tdl Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺ involves: 129 * 129P2/OlaHsd * C57BL/6J	abnormal cell cycle	J:141633
	abnormal DNA repair	J:141633
	early cellular replicative senescence	J:141633

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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