75 phenotypes from 6 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pdss2kd/Pdss2kd B6.CBACaH(CAST)-Pdss2kd	abnormal mitochondrial morphology	J:101779
	dilated renal tubule	J:101779
	tubulointerstitial nephritis	J:101779
Pdss2kd/Pdss2kd CBA/H-Pdss2kd	abnormal enzyme/coenzyme level	J:197578
	abnormal kidney morphology	J:197578
	abnormal mitochondrial ATP synthesis coupled electron transport	J:197578
	abnormal podocyte morphology	J:197578
	abnormal renal glomerulus morphology	J:197578
	abnormal respiratory electron transport chain	J:197578
	albuminuria	J:5232
	colorless urine	J:5232
	decreased hepatocyte mitochondrial DNA content	J:197578
	decreased mitochondrial DNA content	J:197578
	dilated renal tubule	J:5232
	glomerulosclerosis	J:5232, J:197578
	granular kidney	J:5232
	hunched posture	J:5232
	increased mitochondrial DNA content	J:197578
	kidney atrophy	J:5232
	kidney cyst	J:5232, J:197578
	myopathy	J:197578
	oxidative stress	J:197578
	pale kidney	J:5232
	polydipsia	J:5232
	premature death	J:5232
	renal cast	J:5232
	renal tubule atrophy	J:5232
	tubulointerstitial nephritis	J:197578
	weight loss	J:5232
Pdss2kd/Pdss2kd involves: C57BL/6 * CBA/H	abnormal cellular respiration	J:136670
	abnormal glomerular capsule parietal layer morphology	J:170955
	abnormal mitochondrial ATP synthesis coupled electron transport	J:136670
	abnormal podocyte morphology	J:170955
	abnormal renal glomerulus basement membrane morphology	J:170955
	abnormal renal glomerulus morphology	J:170955
	glomerulosclerosis	J:170955
	kidney cyst	J:170955
	podocyte foot process effacement	J:170955
	renal interstitial fibrosis	J:170955
	renal tubule atrophy	J:170955
Pdss2tm1.1Dalg/Pdss2tm1.1Dalg Tg(Zp3-cre)93Knw/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6	embryonic lethality during organogenesis, complete penetrance	J:136670
Pdss2tm1.1Jdhu/Pdss2tm1.2Jdhu Tg(Pax2-cre)1Akg/0 involves: 129 * C57BL/6N * FVB/N	abnormal cell morphology	J:179845
	abnormal cerebellar foliation	J:179845
	abnormal cerebellum development	J:179845
	abnormal cerebellum morphology	J:179845
	abnormal embryonic/fetal subventricular zone morphology	J:179845
	abnormal mitochondrial morphology	J:179845
	abnormal palatine bone horizontal plate morphology	J:179845
	abnormal Purkinje cell migration	J:179845
	abnormal radial glial cell morphology	J:179845
	abnormal skeletal muscle morphology	J:179845
	absent gastric milk in neonates	J:179845
	absent Purkinje cell layer	J:179845
	cerebellum hypoplasia	J:179845
	cerebellum vermis hypoplasia	J:179845
	cleft palate	J:179845
	decreased midbrain size	J:179845
	decreased radial glial cell number	J:179845
	dysphagia	J:179845
	increased neuron apoptosis	J:179845
	micrognathia	J:179845
	midbrain hypoplasia	J:179845
	postnatal lethality, complete penetrance	J:179845
	respiratory distress	J:179845
	short mandible	J:179845
	small cerebellum	J:179845
Pdss2tm1.2Jdhu/Pdss2tm1.2Jdhu involves: 129 * C57BL/6N * FVB/N	embryonic lethality during organogenesis, complete penetrance	J:179845
Pdss2tm1b(EUCOMM)Hmgu/Pdss2+ C57BL/6N-Pdss2tm1b(EUCOMM)Hmgu/H	abnormal tooth morphology	J:211773
	decreased anxiety-related response	J:211773
	decreased thigmotaxis	J:211773
	increased circulating bilirubin level	J:211773
	increased total body fat amount	J:211773
	thrombocytopenia	J:211773
	vertebral fusion	J:211773
Pdss2tm1b(EUCOMM)Hmgu/Pdss2tm1b(EUCOMM)Hmgu C57BL/6N-Pdss2tm1b(EUCOMM)Hmgu/H	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Pdss2tm1Dalg/Pdss2tm1Dalg involves: 129S1/Sv * 129X1/SvJ * C57BL/6	normal homeostasis/metabolism phenotype	J:136670
	normal renal/urinary system phenotype	J:136670
Pdss2tm1Dalg/Pdss2tm1Dalg Hprt1tm1(Pck1-cre)Vhh/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6	normal homeostasis/metabolism phenotype	J:136670
	normal renal/urinary system phenotype	J:136670
Pdss2tm1Dalg/Pdss2tm1Dalg Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal aerobic respiration	J:136670
	abnormal circulating cholesterol level	J:136670
	abnormal energy homeostasis	J:136670
	abnormal mitophagy	J:136670
	abnormal respiratory electron transport chain	J:136670
Pdss2tm1Dalg/Pdss2tm1Dalg Tg(NPHS2-cre)295Lbh/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal renal tubule morphology	J:136670
	albuminuria	J:136670
	dilated renal tubule	J:136670
	increased circulating cholesterol level	J:136670
	tubulointerstitial nephritis	J:136670