About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Wwtr1
WW domain containing transcription regulator 1
MGI:1917649
19 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Lats1tm1Noj/Lats1tm1Noj
Lats2tm1.1Dupa/Lats2tm1.1Dupa
Wwtr1tm1.2Eno/Wwtr1tm1.2Eno
Yap1tm1.1Dupa/Yap1tm1.1Dupa
involves: 129P2/OlaHsd * 129S/SvEv * 129S2/SvPas
abnormal bile duct epithelium morphology J:223215
enlarged liver J:223215
Mob1atm1.1Asuz/Mob1atm1.1Asuz
Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi
Wwtr1tm1Hku/Wwtr1tm1Hku
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: 129P2/OlaHsd * C57BL/6 * DBA
abnormal cholangiocyte morphology J:228499
increased liver weight J:228499
liver fibrosis J:228499
Wwtr1tm1.1Eno/Wwtr1+
Yap1tm1.1Eno/Yap1tm1.1Eno
Tg(Myh6-cre)2182Mds/0
involves: 129S/SvEv * FVB/N
increased cardiomyocyte apoptosis J:200670
myocardium hypoplasia J:200670
postnatal lethality, complete penetrance J:200670
thin myocardium J:200670
Wwtr1tm1.1Eno/Wwtr1tm1.1Eno
Yap1tm1.1Eno/Yap1+
Tg(Myh6-cre)2182Mds/0
involves: 129S/SvEv * FVB/N
abnormal atrial thrombosis J:200670
dilated cardiomyopathy J:200670
premature death J:200670
Wwtr1tm1.1Eno/Wwtr1tm1.1Eno
Yap1tm1.1Eno/Yap1tm1.1Eno
Tg(Myh6-cre)2182Mds/0
involves: 129S/SvEv * FVB/N
abnormal heart morphology J:200670
neonatal lethality, complete penetrance J:200670
Wwtr1tm1Hku/Wwtr1tm1Hku
Yap1tm1Smil/Yap1tm1Smil
involves: 129S/SvEv
embryonic lethality before implantation, complete penetrance J:147050
Wwtr1tm1Hmc/Wwtr1tm1Hmc
Yap1tm1Hmc/Yap1tm1Hmc
Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+
involves: 129 * 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * C57BL/6NCrl
abnormal kidney development J:195266
decreased renal glomerulus number J:195266
decreased renal tubule number J:195266
kidney cyst J:195266

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory